Urology News Archive

Kidney Cancer Parenting Fears Harm Well-Being of Women With Metastatic Cancer

Parenting Fears Harm Well-Being of Women With Metastatic Cancer

Findings based on survey of women with advanced cancer and dependent children.

Prostate Cancer Surgical Overtreatment of Prostate Cancer May Be Decreasing

Surgical Overtreatment of Prostate Cancer May Be Decreasing

Canadian study shows that nearly all men undergoing radical prostatectomy in Eastern Ontario in recent years have clinically significant prostate cancer.

Prostate Cancer Gleason 4+3 vs 3+4 PCa Tied To Higher Risk of Metastasis at Diagnosis

Gleason 4+3 vs 3+4 PCa Tied To Higher Risk of Metastasis at Diagnosis

Men with Gleason score (GS) 4+3 prostate cancer have a 3-fold higher risk of distant metastasis at diagnosis than those with GS 3+4 PCa.

Urology Art Intervention May Be Beneficial for Cancer Patients

Art Intervention May Be Beneficial for Cancer Patients

Brief bedside session associated with improved positive mood, pain scores and decreased anxiety

Prostate Cancer Obesity Linked to Lower Death Risk in Non-metastatic CRPC

Obesity Linked to Lower Death Risk in Non-metastatic CRPC

Obese men with non-metastatic castration-resistant prostate cancer have a 21% decreased risk of death compared with normal weight men, according to a study.

Urology Spermatogenesis Still Occurs in Men With Testicular Cancer

Spermatogenesis Still Occurs in Men With Testicular Cancer

Spermatogenesis often occurs away from tumor; findings may aid fertility planning, sperm retrieval.

Benign Prostatic Hyperplasia (BPH) Certain Anticholinergic Drugs Appear to Raise Dementia Risk

Certain Anticholinergic Drugs Appear to Raise Dementia Risk

Dementia link seen with antidepressant, urological, and anti-Parkinson's drugs.

Urinary Tract Infections (UTI) Lower UTIs More Likely to Resolve With Nitrofurantoin Than Fosfomycin

Lower UTIs More Likely to Resolve With Nitrofurantoin Than Fosfomycin

In a study of women with uncomplicated lower urinary tract infections, 70% of patients treated with nitrofurantoin had complete symptom resolution at 28 days vs 58% of those treated with fosfomycin.

Prostate Cancer Cancer Screening More Likely After a Previous False Positive

Cancer Screening More Likely After a Previous False Positive

Findings for both men and women with a false-positive prostate or breast cancer test result.

Overactive Bladder (OAB) Predictors of Pediatric OAB Healing Time Identified

Predictors of Pediatric OAB Healing Time Identified

Thicker bladder wall and a tower-shaped curve on uroflowmetry are associated with shorter healing periods among pediatric patients with overactive bladder.

Kidney Cancer Odds of Prescribing Drugs Up With Doc Receipt of Payments

Odds of Prescribing Drugs Up With Doc Receipt of Payments

Doctors who receive general payment for cancer drug more likely to prescribe drug marketed by company.

Reproductive Medicine ZIKV RNA Often ID'd in Semen of Men With Symptomatic Infection

ZIKV RNA Often ID'd in Semen of Men With Symptomatic Infection

Drop in ZIKV RNA shedding in semen seen within 3 months after illness onset but can persist longer.

Urology Polypharmacy More Likely for Cancer Survivors

Polypharmacy More Likely for Cancer Survivors

More cancer survivors prescribed 5 or more unique medications, including those with abuse potential

Urinary Incontinence Lasting Outcome Similar for ULS, SSLF for Pelvic Organ Prolapse

Lasting Outcome Similar for ULS, SSLF for Pelvic Organ Prolapse

No significant differences between peri-op behavioral muscle training and usual care at 5 years

Prostate Cancer BRCA Mutations Up Risk for PCa, Other Cancers

BRCA Mutations Up Risk for PCa, Other Cancers

Increased incidence of malignant disease, specifically prostate, melanoma, pancreas, breast cancers

Urinary Tract Infections (UTI) UTI Calculator Predicts Risk of Infant Urinary Tract Infection

UTI Calculator Predicts Risk of Infant Urinary Tract Infection

Calculator reduces testing and decreases the number of urinary tract infections that were missed

Prostate Cancer Survey Highlights Emotional Responses to Prostate Cancer

Survey Highlights Emotional Responses to Prostate Cancer

Sexual dysfunction was a chief complaint among survey respondents with prostate cancer.

Overactive Bladder (OAB) Nasal Spray for Nocturia Is Safe, Effective

Nasal Spray for Nocturia Is Safe, Effective

More patients taking desmopressin decreased their nightly voiding episodes by half or more.

Bladder Cancer Chemo, Immunotherapy Feasible in Metastatic Bladder Cancer

Chemo, Immunotherapy Feasible in Metastatic Bladder Cancer

One-year overall survival of 61% for gemcitabine and cisplatin plus ipilimumab.

Overactive Bladder (OAB) Urodynamics Influence OAB Treatment Decisions

Urodynamics Influence OAB Treatment Decisions

Clinicians' choice of treatment highly correlated with a diagnosis based on urodynamic studies.

Hypogonadism AUA Issues New Guidelines on Testosterone Deficiency

AUA Issues New Guidelines on Testosterone Deficiency

The new guidelines focus on accurate assessment and proper monitoring.

Overactive Bladder (OAB) Nonpharmacologic Therapy Ups Sleep Quality in Women With Nocturia

Nonpharmacologic Therapy Ups Sleep Quality in Women With Nocturia

At least half of women using tibial nerve stimulation or pelvic floor muscle training experienced fewer night awakenings, according to a new study.

Kidney Cancer Relative Visceral Fat Indicates Mortality Risk for Women With RCC

Relative Visceral Fat Indicates Mortality Risk for Women With RCC

An evaluation of patients with clear cell renal cell carcinoma revealed greater risk of death for female patients with high relative visceral fat area (rVFA), highlighting the significance of metabolic differences between men and women.

Urology Most Patients Are Unaware of Cancer Drug Shortages

Most Patients Are Unaware of Cancer Drug Shortages

Majority say they want to know about even minor consequences of cancer drug substitutions

Kidney Cancer Myocarditis Rare Side Effect of Immune Checkpoint Inhibitors

Myocarditis Rare Side Effect of Immune Checkpoint Inhibitors

Myocarditis with ICIs may be more common than initially thought; responds to higher steroid dosages

Prostate Cancer Diet, Exercise With Behavioral Counseling Can Reduce ADT Side Effects

Diet, Exercise With Behavioral Counseling Can Reduce ADT Side Effects

A novel component of an interventional program was cognitive-behavioral counseling administered in a group setting to promote behavioral change.

Prostate Cancer Metabolic Abnormalities Seen in Testicular Cancer Survivors

Metabolic Abnormalities Seen in Testicular Cancer Survivors

HTN, increased LDL and total cholesterol levels; lower rates of decreased HDL levels, abdominal fat

Prostate Cancer Socioeconomics May Not Explain Racial Gap in Prostate Cancer Mortality

Socioeconomics May Not Explain Racial Gap in Prostate Cancer Mortality

In a study, race independently predicted prostate cancer-specific mortality beyond a number of risk factors, including health insurance status.

Hypogonadism Dining Out Linked to Phthalates Exposure in US Population

Dining Out Linked to Phthalates Exposure in US Population

Teen high consumers of food outside the home had 55% higher androgen-disruptor levels.

Kidney Cancer Older Age May Up Risk for RCC-Related Death After Surgery

Older Age May Up Risk for RCC-Related Death After Surgery

The risk of dying from pT1a renal cell carcinoma after partial or radical nephrectomy increases along with patient age.

Prostate Cancer Low-Dose Abiraterone Noninferior for Castration-Resistant PCa

Low-Dose Abiraterone Noninferior for Castration-Resistant PCa

Low-dose AA with low-fat breakfast had greater effect on PSA; similar effect to standard dose

Bladder Cancer Non-Invasive Test for Urothelial Cancer Detection

Non-Invasive Test for Urothelial Cancer Detection

When combined with cytology, UroSEEK detected 95% of patients who developed bladder cancer

Benign Prostatic Hyperplasia (BPH) Expanded Indications Approved for UroLift

Expanded Indications Approved for UroLift

Benign Prostatic Hyperplasia (BPH) Inactivity, Sitting Tied to LUTS in Men

Inactivity, Sitting Tied to LUTS in Men

Low physical activity may increase risk of lower urinary tract symptoms in study of Korean men

Benign Prostatic Hyperplasia (BPH) Factors Affecting PAE Outcomes Identified

Factors Affecting PAE Outcomes Identified

Urology Pregnant Surgical Residents Face Several Challenges

Pregnant Surgical Residents Face Several Challenges

Most women receive 6 weeks or less of maternity leave; most feel leave duration is inadequate.

Prostate Cancer Perioperative Aspirin Use Need Not Prevent RP

Perioperative Aspirin Use Need Not Prevent RP

Perioperative aspirin use should not be considered an absolute contraindication to radical prostatectomy (RP).

Urology Heavier Patient Load Linked to Worse Urologist Ratings

Heavier Patient Load Linked to Worse Urologist Ratings

Poorer ratings seen with increase in Medicare patient load, with rating lowered by 0.04 per 100 patients.

Kidney Cancer Nivolumab Plus Ipilimumab Better for Advanced RCC

Nivolumab Plus Ipilimumab Better for Advanced RCC

Among intermediate- and poor-risk patients, the risk for death was 37% lower with nivolumab plus ipilimumab than with sunitinib.

Urology Periodontitis May Increase Cancer Risk

Periodontitis May Increase Cancer Risk

Strongest associations found for lung and colorectal cancer

Prostate Cancer Finasteride Cuts Prostate Cancer Risk Long Term

Finasteride Cuts Prostate Cancer Risk Long Term

New study shows that men are at lower risk of prostate cancer for years after they stop taking the medication.

Benign Prostatic Hyperplasia (BPH) 5α-Reductase Inhibitors Not Tied to High-Grade Prostate Cancer

5α-Reductase Inhibitors Not Tied to High-Grade Prostate Cancer

A previous study showed that using 5-ARIs to treat benign prostate hyperplasia decreased the risk of low-grade PCa.

Urology Circulating Tumor DNA Assays of Limited Use for Cancer Screening

Circulating Tumor DNA Assays of Limited Use for Cancer Screening

No evidence for circulating tumor DNA assays in early-stage cancer, residual disease detection

Hypogonadism Testosterone Therapy Guidelines Updated

Testosterone Therapy Guidelines Updated

Screening and treating all healthy men older than 65 years with testosterone is discouraged.

Reproductive Medicine Low Sperm Count Linked With Cardiometabolic Conditions, Hypogonadism

Low Sperm Count Linked With Cardiometabolic Conditions, Hypogonadism

Low sperm counts linked to hypogonadism, higher BMI, hypertension, dyslipidemia, metabolic syndrome

Erectile Dysfunction (ED) FDA Warns Against Unapproved Erectile Dysfunction Products

FDA Warns Against Unapproved Erectile Dysfunction Products

Unapproved erectile dysfunction drugs are touted as a "healthy man alternative to the little blue pill."

Reproductive Medicine Daily Pill Promising for Male Birth Control

Daily Pill Promising for Male Birth Control

Dimethandrolone undecanoate lowers testosterone; well tolerated, mild effects of weight gain, lower HDL

Prostate Cancer Dose-Escalated RT Does Not Improve Survival in Intermediate-Risk PCa

Dose-Escalated RT Does Not Improve Survival in Intermediate-Risk PCa

Researchers observed reductions in biochemical failure and distant metastasis rates in patients who had dose-escalated radiation therapy.

Urology Virtual Reality Can Aid Pain Relief From Medical Procedures

Virtual Reality Can Aid Pain Relief From Medical Procedures

VR effective for reducing pain and distress of even extremely painful procedures

Urology VTE Risk High for Emergency General Surgery Patients

VTE Risk High for Emergency General Surgery Patients

Pharmacologic prophylaxis should be considered unless an absolute contraindication exists.

Urology Peripherally Inserted Central Catheter Commonly Used Short-Term

Peripherally Inserted Central Catheter Commonly Used Short-Term

Among patients with short-term peripherally inserted central catheter, about 1 in 10 has a complication

Overactive Bladder (OAB) Nocturia in Men Linked to Metabolic Syndrome, Smoking

Nocturia in Men Linked to Metabolic Syndrome, Smoking

Metabolic syndrome and smoking are associated with 2.5- and 1.7-fold increased odds of moderate or severe nocturia in men with BPH/LUTS.

Urology Vitamin D Status Tied With Cancer Risk

Vitamin D Status Tied With Cancer Risk

Inverse correlation for plasma 25-hydroxyvitamin D concentration with total cancer, liver cancer

Overactive Bladder (OAB) Sleep Disorders in Men Associated With Nocturia

Sleep Disorders in Men Associated With Nocturia

In a study, men with sleep disorders were 23% and 27% more likely to report nocturia and daytime LUTS than men without sleep disorders.

Urology NCCN Recs Go Beyond FDA-Approved Indications

NCCN Recs Go Beyond FDA-Approved Indications

NCCN recommended 47 FDA-approved drugs for 113 indications; 39% were extra recommendations

Kidney Stones Pregnant Stone Formers Have Higher Risk of Gestational Diabetes

Pregnant Stone Formers Have Higher Risk of Gestational Diabetes

Pregnant women with vs without a history of nephrolithiasis are more likely to experience gestational diabetes and preeclampsia.

Urinary Incontinence Urgency Urinary Incontinence Linked to Previous Stroke

Urgency Urinary Incontinence Linked to Previous Stroke

Individuals who had a stroke or transient ischemic attack at age 60 to 64 had a 2-fold higher risk of UUI at age 68 years, a British study found.

Prostate Cancer No Advantages With Aggressive Treatment in Metastatic Prostate Cancer

No Advantages With Aggressive Treatment in Metastatic Prostate Cancer

However, mortality higher with conservative therapy in locally advanced, non-metastatic prostate cancer.

Prostate Cancer Single PSA Screening Has No Effect on Prostate Cancer Mortality

Single PSA Screening Has No Effect on Prostate Cancer Mortality

Findings from a large study of men in the United Kingdom do not support single PSA testing for population-based screening.

Prostate Cancer EBRT+BT+ADT May Be Optimal for High-Grade PCa

EBRT+BT+ADT May Be Optimal for High-Grade PCa

In a study, extremely dose-escalated radiotherapy combined with androgen deprivation therapy offered the best cancer-specific survival among men with Gleason 9-10 prostate cancer.

Overactive Bladder (OAB) Poor Sleep Quality Common in Women With Urgency Incontinence

Poor Sleep Quality Common in Women With Urgency Incontinence

At baseline, women reported an average of 3.9 urgency incontinence episodes per day and 1.3 episodes of nocturia per night.

Hypogonadism Testosterone Replacement Therapy Does Not Raise CV Risks

Testosterone Replacement Therapy Does Not Raise CV Risks

A large study of middle-aged men found that testosterone replacement therapy is associated with a small but significant decrease in cardiovascular risk and an increased risk of obstructive sleep apnea.

Urinary Tract Infections (UTI) Meropenem-vaborbactam Superior for Complicated UTIs

Meropenem-vaborbactam Superior for Complicated UTIs

Overall treatment success occurred in 98.4% of patients receiving meropenem-vaborbactam vs 94% for those receiving piperacillin-tazobactam.

Kidney Cancer Robotic PN May Offer Better Outcomes Than RFA for T1a RCC

Robotic PN May Offer Better Outcomes Than RFA for T1a RCC

Two-year recurrence-free survival was 100% vs 95.2% among robotic surgery and radiofrequency ablation patients, respectively.

Overactive Bladder (OAB) Nocturia May Contribute to Sleep Problems in ADT Recipients

Nocturia May Contribute to Sleep Problems in ADT Recipients

In a 12-month study, men with prostate cancer treated with ADT reported more nocturia episodes than men with prostate cancer treated with prostatectomy alone and men with no history of cancer.

Bladder Cancer Advanced CKD Linked to Worse Radical Cystectomy Outcomes

Advanced CKD Linked to Worse Radical Cystectomy Outcomes

In multivariable analyses, CKD stage G3b or higher was significantly associated with worse progression-free and cancer-specific survival.

Urology Commercial Insurers' Coverage of Infused Chemo Varies by Setting

Commercial Insurers' Coverage of Infused Chemo Varies by Setting

Better reimbursement at hospital outpatient depts, even though drug-level costs lower in doctor's office

Kidney Cancer Small Renal Masses Initially Grow at Variable Rates

Small Renal Masses Initially Grow at Variable Rates

Not reliable predictor of adverse outcomes in those under active surveillance; less variability over time

Urology Brochure Improves Disposal of Unused Opioids After Surgery

Brochure Improves Disposal of Unused Opioids After Surgery

Patients more likely to dispose of unused opioids after getting information and recommendations

Prostate Cancer MRI May Help Cut Down on Unnecessary Prostate Biopsies

MRI May Help Cut Down on Unnecessary Prostate Biopsies

Multiparametic MRI findings added to conventional clinical predictors decreases the number of false-positive biopsy results without increasing the number of clinically significant tumors left undiagnosed, study finds.

Urology Placebo May Ease Fatigue in Cancer Survivors

Placebo May Ease Fatigue in Cancer Survivors

Reductions seen in fatigue symptom severity and fatigue-related quality of life disruption

Urology Adolescent Cancer Survivors Have Inadequate Follow-up Care

Adolescent Cancer Survivors Have Inadequate Follow-up Care

Many young adult cancer survivors do not follow up properly, independent of disease type or insurance.

Kidney Stones Kidney Stone Diagnoses Up From 1984 to 2012

Kidney Stone Diagnoses Up From 1984 to 2012

The increase included both symptomatic and asymptomatic kidney stones

Urology Model Stratifies Long Bone Metastases Pts By Survival

Model Stratifies Long Bone Metastases Pts By Survival

Model includes 4 prognostic categories with clinical consequences to predict median survival.

Prostate Cancer FDA Oks Drug for Non-metastatic Castration-Resistant Prostate Cancer

FDA Oks Drug for Non-metastatic Castration-Resistant Prostate Cancer

Apalutamide prolonged metastasis-free survival by 2 years compared with placebo.

Bladder Cancer Model Predicts Survival in Urothelial Cancer With Immunotherapy

Model Predicts Survival in Urothelial Cancer With Immunotherapy

Model, based on 6 factors, predicts overall survival for patients treated with atezolizumab

Bladder Cancer Active Surveillance Reasonable for NMIBC

Active Surveillance Reasonable for NMIBC

Appears to be a cost-effective strategy for patients with small size, stage pTa or pT1a recurrent tumors

Bladder Cancer Atezolizumab Safe, Beneficial Long-Term in mUC

Atezolizumab Safe, Beneficial Long-Term in mUC

In a 3-year study, toxic effects of atezolizumab remained manageable and responses durable.

Prostate Cancer Inclusion Criteria for PCa Trials Inadvertently Exclude Blacks

Inclusion Criteria for PCa Trials Inadvertently Exclude Blacks

Trials sponsored by academic investigators, cooperative groups more likely to use these criteria

Bladder Cancer Biopsy, Pathology Results Often Differ in UTUC

Biopsy, Pathology Results Often Differ in UTUC

Study results serve as a caution against relying on ureteroscopic biopsy to establish tumor grade and stage, researchers say.

Prostate Cancer Adverse Prostate Cancer Pathology Accurately Predicted With MRI

Adverse Prostate Cancer Pathology Accurately Predicted With MRI

Multiparametric MRI has high positive and negative predictive values for extracapsular extension, seminal vesicle invasion, lymph node involvement, and high-risk Gleason score.

Bladder Cancer E-Cigarette Smoke Possibly Carcinogenic to Lung, Bladder

E-Cigarette Smoke Possibly Carcinogenic to Lung, Bladder

Nicotine and nicotine-derived nitrosamine ketone enhance mutational susceptibility in human cells.

Prostate Cancer Telementoring Useful for Teaching Robotic Surgery

Telementoring Useful for Teaching Robotic Surgery

The technology facilitates teaching of advanced surgical skills, delivery of care to underserved

Prostate Cancer Brachytherapy Alone May Be Sufficient for More Risky PCa Cases

Brachytherapy Alone May Be Sufficient for More Risky PCa Cases

The investigators observed no difference in mortality between BT alone and BT plus ADT and/or EBRT supplemental therapy.

Bladder Cancer Post-Cystectomy UTI Risk Linked to Comorbidities

Post-Cystectomy UTI Risk Linked to Comorbidities

A Charlson Comorbidity Index score of 2 or higher is an independent risk factor for urinary tract infections within 90 days following radical cystectomy for bladder cancer, study finds.

Benign Prostatic Hyperplasia (BPH) BPH Risk May Be Lower Among Allopurinol Users

BPH Risk May Be Lower Among Allopurinol Users

Men using allopurinol had a 22% lower risk of a BPH diagnosis.

Urinary Incontinence Urinary Incontinence Common Before, During Pregnancy

Urinary Incontinence Common Before, During Pregnancy

An Irish study found that 34.8% and 38.7% of nulliparous women experienced urine leakage before and during pregnancy, respectively.

Kidney Stones Kidney Stone Treatment Better With Ureterorenoscopy

Kidney Stone Treatment Better With Ureterorenoscopy

For renal calculi 5 to 20 mm in diameter, treatment with flexible ureterorenoscopy was associated with higher stone-free and freedom from reintervention rates vs ESWL.

Erectile Dysfunction (ED) Statin, BP Lowering Meds Don't Improve Erectile Function

Statin, BP Lowering Meds Don't Improve Erectile Function

No significant effect for rosuvastatin, CandHCTZ, or both versus placebo in men aged 55 years.

Urology Death Risk Rises as Day of Surgery Approaches Weekend

Death Risk Rises as Day of Surgery Approaches Weekend

Mortality after elective surgery increases in graded manner as day of surgery approaches weekend.

Prostate Cancer LDR Brachytherapy for Prostate Cancer Offers Excellent Survival

LDR Brachytherapy for Prostate Cancer Offers Excellent Survival

In a study, the 17-year prostate cancer-specific and biochemical failure-free survival rates were 97% and 79%, respectively.

Bladder Cancer MRI Differentiates Low-Grade Bladder Tumors

MRI Differentiates Low-Grade Bladder Tumors

Diffusion-weighted imaging and use of higher field strengths further improve accuracy.

Prostate Cancer Adjuvant Better Than Early Salvage RT for Some High-risk PCa Patients

Adjuvant Better Than Early Salvage RT for Some High-risk PCa Patients

Adjuvant radiotherapy was associated with lower risks for biochemical failure and distant metastases and increased overall survival in patients with adverse pathologic features found after radical prostatectomy.

Erectile Dysfunction (ED) ED Risk Is Associated With Handgrip Strength

ED Risk Is Associated With Handgrip Strength

Men with greater handgrip strength have a lower risk of erectile dysfunction (ED), new findings suggest.

Bladder Cancer Adjuvant Radiation Therapy May Improve Survival After Cystectomy

Adjuvant Radiation Therapy May Improve Survival After Cystectomy

The locoregional recurrence-free survival rate at 2 years was significantly higher for patients treated with chemotherapy plus RT versus those treated with chemotherapy alone.

Prostate Cancer Obesity, Metabolic Syndrome Increases Risk for PCa Recurrence

Obesity, Metabolic Syndrome Increases Risk for PCa Recurrence

Following radical prostatectomy, higher BMI increases risk of recurrence for prostate cancer.

Erectile Dysfunction (ED) Aspirin Found Effective for Erectile Dysfunction

Aspirin Found Effective for Erectile Dysfunction

Erectile function among men with vasculogenic erectile dysfunction improved significantly after 6 weeks of treatment with an aspirin dosage of 100 mg/day.

Bladder Cancer Mortality High Among HD Patients Who Undergo Bladder Cancer Surgery

Mortality High Among HD Patients Who Undergo Bladder Cancer Surgery

Patients on hemodialysis who undergo radical cystectomy for bladder cancer have 30-day and 5-year mortality rates of 9.3% and 87.9%, respectively, study finds.

Urinary Tract Infections (UTI) Sulfonamides, Nitrofurantoin Prescribed for UTI in Pregnant Women

Sulfonamides, Nitrofurantoin Prescribed for UTI in Pregnant Women

Nitrofurantoin, trimethoprim-sulfamethoxazole prescribed first trimester despite ACOG recs.

Urology Optimizing Quality of Life in Seniors With Cancer

Optimizing Quality of Life in Seniors With Cancer

Persistent symptoms, comorbidities, leisure-time physical activity, financial challenges deemed key factors

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