Urology News Archive
A "weekday-on and weekend-off regimen" improves relative dose intensity compared with the conventional regimen, a study found.
New meta-analysis shows adjuvant intravesical gemcitabine and bacillus Calmette-Guérin do not differ significantly with respect to risk of recurrence, progression, and adverse events.
Men prescribed 3 different phosphodiesterase type 5 inhibitors had nearly 3-fold increased odds of having a Charlson Comorbidity Index of 1 or higher than men not prescribed the drugs.
At a major tertiary referral center, the use of radical prostatectomy for insignificant prostate cancer decreased from 15% in 2009 to 3% in 2016, a study found.
In a study, 8 mg of silodosin daily for 12 weeks was associated with a significant reduction in nocturia episodes.
A recent paper provides 8 questions to ask patients to elicit information that enables targeted treatment of nocturia.
A patient's risk of suicide is doubled within the first year following a prostate cancer diagnosis, according to a new meta-analysis.
Study of Korean radical prostatectomy patients showed that those who were obese had significant increased odds of biochemical recurrence and cancer-specific mortality
Small study found that 2 mg of melatonin taken at bedtime did not significantly decrease the mean number of nocturia episodes vs placebo.
Clinicians should assess whether women experience urinary incontinence and whether it affects their health, function, and quality of life.
Cytoreductive radical prostatectomy (RP) for metastatic prostate cancer (PCa) is associated with higher complication rates and longer hospital stays than RP for non-metastatic PCa.
Physicians increasingly are prescribing high dose and very high dose radiation therapy after radical prostatectomy despite an absence of randomized trials supporting the practice.
Patients may benefit from earlier lines of enzalutamide for the treatment of metastatic castration-resistant prostate cancer.
In a study, the off-clamp approach to partial nephrectomy also was associated with lower risk for acute kidney injury.
Zemdri carries a Boxed Warning describing reports of nephrotoxicity, ototoxicity, and neuromuscular blockade, as well as fetal harm if administered during pregnancy.
Circulating blood biomarkers related to angiogenesis may help clinicians predict who will have a robust response to sunitinib.
Stereotactic body radiation therapy achieves good local control of metastases in patients with recurrent prostate cancer following primary treatment.
Shorter PSA double times are associated with worse disease-specific, metastasis-free, and overall survival, study finds.
Radiation therapy dose escalation, pelvic lymph node irradiation, and hormone therapy duration are prescribed based on patient and tumor characteristics.
Men in the bottom 10th of free testosterone level vs those with higher levels were found to have a 23% decreased risk of prostate cancer.
Among patients undergoing radical cystectomy, female sex is independently associated with a 21% increased odds of surgical site infections compared with male sex.
Among women who reported urinary incontinence in a baseline survey, 13.1% reported urinary leakage 4 or more times per week.
Younger men with prostate cancer are less likely to experience Gleason score upgrading and pathologic progression on repeat biopsy.
Significant improvements in symptoms, peak flow rate, and post-void residual volume observed in men with prostate volumes of 80 to 150 cc.
Widowed patients with bladder urothelial carcinoma have the worst 5-year cancer-specific survival rates among unmarried patients.
Obesity is associated with an increased likelihood of clear cell and possibly chromophobe renal cell carcinoma.
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The likelihood of aggressive kidney tumor histology increased along with tumor size, a new study found.
According to researchers, 57.3% of men who underwent salvage robot-assisted radical prostatectomy were pad-free at 12 months.
New study shows no significant difference in overall survival between 18 and 36 months of androgen deprivation therapy used in combination with radiation therapy.
Solifenacin plus tamsulosin improved all symptoms on the ureteral stent symptom questionnaire.
Inconsistencies exist between CDC and NCCN opioid guideline recommendations.
Women presenting with lower urinary tract symptoms cluster into 4 distinct symptom groups, according to a recent study.
Regardless of treatment modality, men with Gleason 10 prostate cancer have high 5-year overall survival rates, new study finds.
Early study results are encouraging, but high-quality data that validate PET/CT against a reliable reference standard are lacking.
MRI with targeted prostate biopsy plus systematic biopsy fails to improve detection of upgrading in men on active surveillance for prostate cancer vs systematic biopsy alone.
This latest approval now makes enzalutamide the only FDA-approved oral medication indicated for both metastatic and nonmetastatic castration-resistant prostate cancer.
British investigators concluded that urine cytology misses a significant number of muscle-invasive bladder cancers.
Bladder hydrodistention with fulguration of Hunner lesions reduced nocturia in IC patients with or without nocturnal polyuria.
Recurrence rate was 26.4% among patients who had overnight continuous saline irrigation following transurethral resection of bladder tumor vs 38.2% among those who did not.
The moment is here: You're opening your own nephrology or urology practice. How can you make it grow?
Exclusion of women from upper echelons of medicine may have real implications for patient care.
Over a 25-year period, the proportion of patients with high-risk clinical T1 tumors increased by nearly 20% and clinical tumor size decreased from 8.4 to 6.2 cm, an Italian study found.
Pulmonary embolism is associated with GnRH agonist use and orchiectomy.
The impact of partial brachytherapy on metastasis and disease-specific mortality is unclear.
Robotic PN was associated with significantly lower rates of complications, cancer recurrence, and mortality compared with open and laparoscopic PN.
Incidence of tx-emergent small-cell neuroendocrine prostate cancer 17% among those with mCRPC.
From 2013 to 2016, the relative decrease in testosterone prescriptions was 48% among established testosterone users and 62% among new users.
No differences seen with other fat volume measures between recurring, first-time stones.
Failure-free survival was 88% at 5 years among patients with nonmetastatic prostate cancer who underwent focal therapy with high-intensity focused ultrasound.
The association between obesity, age, and renal cell carcinoma prognosis requires additional investigation.
The updates come after the Agency made the decision to limit the use of these agents as monotherapy in patients with metastatic urothelial cancer who have not received prior therapy and who have low expression of the protein programmed death ligand 1 (PD-L1).
Among men aged 20-39 years, those in the top quartile of sugar-sweetened beverage intake had 2.3-fold greater odds of low testosterone than those in the bottom quartile.
aBSI validated as prognostic biomarker of survival in metastatic castration-resistant prostate cancer
ICU and hospital mortality were lower for patients with cancer versus those without cancer.
More conservative management and active surveillance utilized at VA hospitals from 2005 to 2015.
Collagenase clostridium histolyticum therapy is associated with significantly worse improvement in penile curvature in men with calcified plaques.
Bladder preservation for MIBC is associated with a higher mortality rate and greater costs compared with radical cystectomy.
Metformin plus androgen deprivation therapy is associated with a lower death risk vs ADT alone in men without diabetes, study of US veterans shows.
Nocdurna carries a Boxed Warning for hyponatremia.
Men receiving enzalutamide plus ADT had a significant 71% lower risk for metastasis or death compared with men receiving placebo plus ADT.
Plazomicin, an aminoglycoside, was approved for treating complicated urinary tract infections in adults due to certain Enterobacteriaceae.
Post-traumatic stress symptoms also linked to lower risk of readmission in hospitalized CA patients.
Children who migrated to the UK from Bangladesh before puberty and Bangladeshis born in the UK had significantly higher levels of testosterone compared with life-long residents of Bangladesh.
Percutaneous ablation offers cancer-related outcomes similar to those of radical nephrectomy but with a lower likelihood of long-term renal insufficiency and complications.
Only half of patients with initial treatment success maintain benefits at 2 years.
In a randomized study, patients who underwent robotic-assisted and open radical cystectomy had similar 2-year progression survival rates.
In a phase 3 trial, Prostvac-V/F did not significantly prolong overall survival among men with asymptomatic or minimally symptomatic mCRPC.
Females have worse disease-free, cancer-specific, overall survival versus males with bladder cancer.
Men with advanced prostate cancer at diagnosis have an elevated risk of spinal cord compression, renal failure, and other cancer-related morbidities.
Treatment appeared to reduce fall risk among older adults.
The passage rate for ureteral stones less than 9 mm in diameter did not differ significantly between tamsulosin and placebo recipients, study finds.
Study confirms associations between nocturia and older age, female sex, overactive bladder, and diabetes.
Study participants with acute urinary retention after TRUS-guided prostate biopsy were 4.5 times more likely to skip a recommended re-biopsy than men who had no initial biopsy-related complications.
Perioperative red blood cell transfusion linked to increased adjusted odds of VTE, DVT, PE.
Over 12 weeks of treatment, the mean number of nocturia episodes decreased by 1.1 and 0.9 in men who were and were not bothered by their symptoms, a non-significant difference between groups.
Clinicians can rest easier about recommending finasteride to more men, according to experts.
Men with erectile dysfunction (ED) are almost twice as likely to experience a cardiovascular event as those without ED.
Those with worse emotional distress also report worse urinary, sexual, bowel functions.
If externally validated, bpMRI could be used to triage men for prostate biopsy.
Fulphila, biosimilar to Neulasta, helps reduce risk of infection during cancer treatment.
Abiraterone plus prednisone was associated with significantly greater PSA progression-free survival among patients who are black compared with white patients.
Enzalutamide decreases the risk of clinically meaningful deterioration in HRQoL compared with placebo in men with non-metastatic CRPC, new study finds.
98.4% of respondents report moderate, severe shortages of morphine, hydromorphone, fentanyl.
New findings from the CARMENA trial contradict previous research showing better survival from cytoreductive nephrectomy followed by targeted therapy.
Greater decrease in total UI frequency with yoga intervention versus time-and-attention control group.
May be as effective as full-dose direct oral anticoagulants for extended-duration treatment.
"We are confident this guideline is fully aligned with the latest science on treatments for patients with non-metastatic and metastatic CRPC," said Michael Cookson, MD, member of the 2018 amendment panel.
Benefit of palliative radiation for bone metastasis across age groups; older age should not preclude tx.
Findings for men with intermediate- and high-risk prostate cancer.
Lower rate of VTE recurrence, but higher clinically relevant non-major bleeding versus dalteparin.
In a meta-analysis, smokers had an 89% greater risk of dying from prostate cancer compared with nonsmokers.
The approval of Yonsa was based on 2 randomized, placebo-controlled, multicenter Phase 3 studies in patients with mCRPC.
Cryoablation also cuts the need for opioids at 24 hours post-treatment and at 3 months.
Sharpest decrease seen in privately insured men after 2011.
Clinicians tend to focus on the number of voids, but patients worry more about interrupted sleep.
Magnitude of benefit of immune checkpoint inhibitors sex-dependent for patients with advanced cancers.
Compared with whites, blacks, and Hispanics, Middle Easterners are more likely to have predominantly calcium oxalate monohydrate stones, but less likely to have hydroxyapatite stones.
Enhanced therapeutic effect of bacillus Calmette-Gurin tx in non-muscle invasive bladder cancer.
Nine donations were confirmed positive; 6 of these had travelled to ZIKV-active areas.
Renal and Urology News Articles
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NEPHROLOGY & UROLOGY NEWS
- Acute Kidney Injury (AKI)
- Chronic Kidney Disease (CKD)
- Contrast Nephropathy
- Cardiovascular Disease (CVD)
- Diabetic Nephropathy
- End-stage Renal Disease (ESRD)
- Lupus Nephritis
- Peritoneal Dialysis
- Secondary Hyperparathyroidism (SHPT)