Urology News Archive
UGN-1 is an investigational formulation of mitomycin, delivered to patients using standard intravesical catheters.
Local control, cancer-specific survival at 2 years similar for patients with solitary, bilateral kidneys
New multidisciplinary guideline for early-stage prostate cancer developed by 3 professional societies.
Results from phase 2 study in patients with multidrug-resistant Gram-negative uropathogens.
At the time of diagnosis of renal cell carcinoma, blacks had 33% lower odds of regional disease compared with whites, a new study found.
The 3-year survival rate was 81% for patients who underwent EBRT plus standard care vs 73% for those who had standard care alone.
Trials show high survival rates, freedom from recurrence for low-, intermediate-risk prostate cancer.
3 percent of midurethral mesh slings for stress urinary incontinence removed by 9 years
Radiation dose not impacted with light or moderate use of skin treatments, regardless of beam energy, incidence
Long-term data show a local disease recurrence rate of 2.1% at 10 years.
Long-term oncologic outcomes of patients with sporadic RCC who underwent robotic tumor enucleation suggest the procedure is safe.
Among prostate cancer patients, androgen deprivation therapy (ADT) recipients are 34% more likely to experience any osteoporotic fracture than those who do not receive ADT.
New findings could help explain why men of African ancestry are more likely than white men to die from prostate cancer.
International Continence Society (ICS) standards offer useful guidance for nocturia management, according to the authors of a new report.
A midlife PSA value above the 90th percentile was associated with greater risk of total and aggressive prostate cancer in black men.
Older patients benefit from treatment of superficial bladder cancer even if they have multiple chronic conditions, a new study suggests.
In a study, advanced glycation end products were significantly higher in people with nocturia.
In a study, androgen deprivation therapy did not increase risks for vascular or any other form of dementia among men with prostate cancer who underwent definitive radiation therapy.
In a recently published study, external beam radiation therapy for localized prostate cancer was associated with a 35% increased risk of bladder cancer compared with radical prostatectomy.
In a study, nighttime voiding significantly correlated with smaller dips in nocturnal blood pressure.
Having 3 or more voids per night was associated with 72% excess death risk.
New study reveals a 29% prevalence of erectile dysfunction, a proportion higher than that of the general population.
A combination of age, comorbidity, and PSA doubling time can risk stratify cause of death among men with non-metastatic castration-resistant prostate cancer, study suggests.
Myocardial infarction following the kidney stone procedure is twice as likely among patients with 3 to 4 components of metabolic syndrome vs no components.
Men in Puerto Rico have higher prostate cancer incidence rates than other Hispanics, non-Hispanic whites.
In a study, men with prostate cancer who received androgen deprivation therapy did not have a lower subsequent risk of developing bladder cancer.
Depletion of Lactobacillus iners in the bladder appears to increase the risk of urinary tract infection following urogynecologic surgery, study finds.
Study of patients with clinical T1a renal cell carcinoma shows that those who undergo renal mass biopsy have only a 1.2% rate of upstaging to pT3a perinephric fat involvement.
Increased facility use of mesh augmentation impacts risk of repeat prolapse repair surgery
At 6 months, rates for provoked, unprovoked, cancer-related VTE are 6.8, 6.92, 9.06 per 100 person-years
Propensity score-matched analysis shows that radical and partial nephrectomy for cT1 renal cell carcinoma are associated with similar cancer-specific and all-cause mortality, a study found.
During a 12-month study, women who drank 1.5 L of water daily in addition to their usual fluid intake reduced their mean number of cystitis episodes nearly by half.
Medium-term oncologic results are comparable to those of radical prostatectomy and radiation therapy, according to investigators.
Older age, male sex, and higher T stage are associated with an increased risk of having bone metastases at initial diagnosis of renal cell carcinoma, study finds.
Only 11% of private insurers in the United States cover prostate MRI in biopsy-naïve patients with suspect prostate cancer.
Correlates of receiving prescription include female sex, specific physician specialty, geographic region
Radical prostatectomy plus adjuvant radiotherapy is associated with better cancer-specific and overall survival than radiotherapy plus androgen deprivation therapy in patients with locally or regionally advanced prostate cancer.
Development of kidney stones is 6.2-fold more likely among patients with persistent hyponatremia than those without a history of hyponatremia.
Percutaneous nephrostomy is associated with better outcomes than retrograde ureteral stent placement in patients with hydronephrosis secondary to ureteric stones.
Low ureteral wall thickness is associated with a greater likelihood of spontaneous passage of ureteral stones 10 mm or smaller in diameter, according to a new study.
Partial vs radical nephrectomy is associated with an overall survival advantage among patients with RCC tumors 4 cm or smaller and many patients with larger tumors.
Men in the highest vs lowest tertile of total cholesterol had a 42% increased risk of Gleason 8-10 prostate cancer, Finnish study finds.
Some prostate cancer cells lack androgen receptor, and they proliferate faster than those that express androgen receptor under androgen-deficient conditions.
Epstein-Barr virus infection found much more frequently in patients with vs without IC/BPS and Hunner lesions or controls with stress urinary incontinence.
A neutrophil-lymphocyte ratio below 4 is associated with significantly longer survival among patients with non-poor-risk metastatic renal cell carcinoma.
A study of 400,887 men in an integrated health system, the first to evaluate various PSA screening intervals and age groups, concluded that yearly screening is the interval of choice.
New analysis of the SPARTAN trial shows that apalutamide maintains health-related quality of life while lowering the risk of metastasis.
Australian study shows 8-year overall survival and biochemical relapse-free rates of 78.4% and 68.1%, respectively.
Men who received androgen deprivation therapy for prostate cancer were 54% more likely to be diagnosed with non-alcoholic fatty liver disease than those who did not, a study found.
Finnish study of individuals with type 2 diabetes reveals a 17% and 42% higher incidence of bladder and kidney cancer, respectively, compared with the general population.
Higher rates of complete response observed in MIBC patients who received a dose-dense combination of methotrexate, vinblastine, doxorubicin, and cisplatin rather than the standard gemcitabine plus cisplatin or carboplatin.
In a German study of patients starting first-line systemic therapy for advanced renal cell carcinoma, patients with a low BMI were twice as likely to die as those with a high BMI.
Recurrent kidney stone formers are at higher risk of end-stage renal disease than patients who form incident symptomatic stones, study finds.
The risk being lost to follow-up while on active surveillance for prostate cancer is higher among blacks than whites, according to a study.
Lower urinary tract symptom severity in men is associated with detectable bacteria in urine obtained via catheter, new study suggests.
Low-dose-rate brachytherapy is associated with excellent long-term biochemical control and survival, new study finds.
Even low cumulative exposure to physical strain at work is associated with a decreased risk of prostate cancer, study finds.
In a study, men with low-risk prostate cancer were nearly 2-fold more likely to be managed with observation if they had a prostate MRI during the diagnostic work-up.
Prospective study at Johns Hopkins shows excellent oncologic outcomes and preserved mental quality of life for all patients regardless of management strategy, with worse renal function after radical nephrectomy.
Urinary stone formation in adults increases the odds of asthma by 26%, according to a study.
A "weekday-on and weekend-off regimen" improves relative dose intensity compared with the conventional regimen, a study found.
New meta-analysis shows adjuvant intravesical gemcitabine and bacillus Calmette-Guérin do not differ significantly with respect to risk of recurrence, progression, and adverse events.
Men prescribed 3 different phosphodiesterase type 5 inhibitors had nearly 3-fold increased odds of having a Charlson Comorbidity Index of 1 or higher than men not prescribed the drugs.
At a major tertiary referral center, the use of radical prostatectomy for insignificant prostate cancer decreased from 15% in 2009 to 3% in 2016, a study found.
In a study, 8 mg of silodosin daily for 12 weeks was associated with a significant reduction in nocturia episodes.
A recent paper provides 8 questions to ask patients to elicit information that enables targeted treatment of nocturia.
A patient's risk of suicide is doubled within the first year following a prostate cancer diagnosis, according to a new meta-analysis.
Study of Korean radical prostatectomy patients showed that those who were obese had significant increased odds of biochemical recurrence and cancer-specific mortality
Small study found that 2 mg of melatonin taken at bedtime did not significantly decrease the mean number of nocturia episodes vs placebo.
Clinicians should assess whether women experience urinary incontinence and whether it affects their health, function, and quality of life.
Cytoreductive radical prostatectomy (RP) for metastatic prostate cancer (PCa) is associated with higher complication rates and longer hospital stays than RP for non-metastatic PCa.
Physicians increasingly are prescribing high dose and very high dose radiation therapy after radical prostatectomy despite an absence of randomized trials supporting the practice.
Patients may benefit from earlier lines of enzalutamide for the treatment of metastatic castration-resistant prostate cancer.
In a study, the off-clamp approach to partial nephrectomy also was associated with lower risk for acute kidney injury.
Zemdri carries a Boxed Warning describing reports of nephrotoxicity, ototoxicity, and neuromuscular blockade, as well as fetal harm if administered during pregnancy.
Circulating blood biomarkers related to angiogenesis may help clinicians predict who will have a robust response to sunitinib.
Stereotactic body radiation therapy achieves good local control of metastases in patients with recurrent prostate cancer following primary treatment.
Shorter PSA double times are associated with worse disease-specific, metastasis-free, and overall survival, study finds.
Radiation therapy dose escalation, pelvic lymph node irradiation, and hormone therapy duration are prescribed based on patient and tumor characteristics.
Men in the bottom 10th of free testosterone level vs those with higher levels were found to have a 23% decreased risk of prostate cancer.
Among patients undergoing radical cystectomy, female sex is independently associated with a 21% increased odds of surgical site infections compared with male sex.
Among women who reported urinary incontinence in a baseline survey, 13.1% reported urinary leakage 4 or more times per week.
Younger men with prostate cancer are less likely to experience Gleason score upgrading and pathologic progression on repeat biopsy.
Significant improvements in symptoms, peak flow rate, and post-void residual volume observed in men with prostate volumes of 80 to 150 cc.
Widowed patients with bladder urothelial carcinoma have the worst 5-year cancer-specific survival rates among unmarried patients.
Obesity is associated with an increased likelihood of clear cell and possibly chromophobe renal cell carcinoma.
Hiring the right people is key to growing your nephrology or urology practice. How can you assemble a top-notch staff?
The likelihood of aggressive kidney tumor histology increased along with tumor size, a new study found.
According to researchers, 57.3% of men who underwent salvage robot-assisted radical prostatectomy were pad-free at 12 months.
New study shows no significant difference in overall survival between 18 and 36 months of androgen deprivation therapy used in combination with radiation therapy.
Solifenacin plus tamsulosin improved all symptoms on the ureteral stent symptom questionnaire.
Inconsistencies exist between CDC and NCCN opioid guideline recommendations.
Women presenting with lower urinary tract symptoms cluster into 4 distinct symptom groups, according to a recent study.
Regardless of treatment modality, men with Gleason 10 prostate cancer have high 5-year overall survival rates, new study finds.
Early study results are encouraging, but high-quality data that validate PET/CT against a reliable reference standard are lacking.
MRI with targeted prostate biopsy plus systematic biopsy fails to improve detection of upgrading in men on active surveillance for prostate cancer vs systematic biopsy alone.
This latest approval now makes enzalutamide the only FDA-approved oral medication indicated for both metastatic and nonmetastatic castration-resistant prostate cancer.
British investigators concluded that urine cytology misses a significant number of muscle-invasive bladder cancers.
Bladder hydrodistention with fulguration of Hunner lesions reduced nocturia in IC patients with or without nocturnal polyuria.
Recurrence rate was 26.4% among patients who had overnight continuous saline irrigation following transurethral resection of bladder tumor vs 38.2% among those who did not.
Renal and Urology News Articles
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