Urinary Tract Infection
Abx-Resistant Enterobacteriaceae Tied to Clinical Failure in UTI
November 08, 2018Poor clinical outcomes linked to extended spectrum cephalosporin-resistant Enterobacteriaceae.
PCR Test Bests Urine Cultures for UTI Pathogen Detection
November 04, 2018A multiplex polymerase chain reaction assay detected bacteria species missed by traditional urine culture as well as more fastidious bacteria.
Fluoroquinolones Tied to Increased Risk for Arrhythmia, CV Mortality
November 02, 2018To investigate the risk of cardiovascular adverse effects associated with this antibiotic class, researchers conducted a systematic review, meta-analysis, and network meta-analysis using studies identified through a search of MEDLINE, EMBASE, and the Cochrane Library.
In Complicated UTI, Cefiderocol Noninferior to Imipenem-Cilastin
October 31, 2018Results from phase 2 study in patients with multidrug-resistant Gram-negative uropathogens.
UTI Risk After Urogynecologic Surgery Linked to Bladder Microbiome
October 03, 2018Depletion of Lactobacillus iners in the bladder appears to increase the risk of urinary tract infection following urogynecologic surgery, study finds.
Recurrent Cystitis Possibly Preventable by Drinking More Water
October 01, 2018During a 12-month study, women who drank 1.5 L of water daily in addition to their usual fluid intake reduced their mean number of cystitis episodes nearly by half.
Zemdri Now Treats Complicated UTI, Pyelonephritis
August 08, 2018Zemdri carries a Boxed Warning describing reports of nephrotoxicity, ototoxicity, and neuromuscular blockade, as well as fetal harm if administered during pregnancy.
FDA Requires Safety Label Changes for Fluoroquinolones
July 13, 2018Changes will describe hypoglycemic coma and clarify and identify mental health side effects.
FDA Approves Drug for Complicated UTIs
June 27, 2018Plazomicin, an aminoglycoside, was approved for treating complicated urinary tract infections in adults due to certain Enterobacteriaceae.
Prediction tool for urinary tract infections in preverbal children
May 01, 20181. The study reports the development of a clinical and biochemical prediction tool for assessing the risk of urinary tract infection in preverbal children with fever. The model developed accurately predicted which patients may need further testing based on clinical variables, and who may need antibiotics therapy based on urine analysis supplement. 2. In a []
Lower UTIs More Likely to Resolve With Nitrofurantoin Than Fosfomycin
April 26, 2018In a study of women with uncomplicated lower urinary tract infections, 70% of patients treated with nitrofurantoin had complete symptom resolution at 28 days vs 58% of those treated with fosfomycin.
UTI Calculator Predicts Risk of Infant Urinary Tract Infection
April 17, 2018Calculator reduces testing and decreases the number of urinary tract infections that were missed
Meropenem-vaborbactam non-inferior to piperacillin-tazobactam for complicated urinary tract infections: The TANGO I trial
March 02, 20181. In this randomized controlled trial, meropenem-vaborbactam was found to be non-inferior to piperacillin-tazobactam for treating complicated urinary tract infections (UTIs). 2. The rate of adverse events were similar between groups. Evidence Rating Level: 1 (Excellent) Study Rundown: As carbapenemases become more prevalent among organisms that cause complicated Urinary Tract Infections (UTIs), the need for []
Meropenem-vaborbactam Superior for Complicated UTIs
March 02, 2018Overall treatment success occurred in 98.4% of patients receiving meropenem-vaborbactam vs 94% for those receiving piperacillin-tazobactam.
Post-Cystectomy UTI Risk Linked to Comorbidities
February 06, 2018A Charlson Comorbidity Index score of 2 or higher is an independent risk factor for urinary tract infections within 90 days following radical cystectomy for bladder cancer, study finds.
Sulfonamides, Nitrofurantoin Prescribed for UTI in Pregnant Women
January 26, 2018Nitrofurantoin, trimethoprim-sulfamethoxazole prescribed first trimester despite ACOG recs.
Confusion Tied to Antibiotics Rx in Nursing Home Residents With UTI
January 25, 2018Confusion independently associated with receipt of antibiotics for UTI in nursing home residents.
Urinalysis Accurately Diagnoses UTIs in Febrile Infants
January 23, 2018Study shows test is sensitive and specific in infants younger than 60 days old.
Cyclists Have No Worse Sexual or Urinary Functions
January 18, 2018No worse sexual or urinary function, but incidence of urethral stricture higher than swimmers/runners.
Bladder, Bowel Dysfunction More Likely in Girls vs Boys
January 08, 2018New analysis finds that female sex and non-dilating vesicoureteral reflux are independently associated with an increased risk of bladder and bowel dysfunction.
NSAID vs Antibiotic for Symptomatic Urinary Tract Infection
November 13, 2017Symptom resolution at day 3 was met by 54% in the diclofenac group vs 80% in the norfloxacin group.
Meat Often Contains Bacteria Linked to UTIs
October 10, 2017Almost one-fourth of retail poultry contains E. coli strains associated with urinary tract infections
Recurrent UTIs Worsen Kidney Transplant Outcomes
October 05, 2017Kidney transplant recipients who experience recurrent urinary tract infections are at increased risk of graft failure and death.
Drug Approved for Complicated Urinary Tract Infections
August 31, 2017Vabomere, which combines meropenem and vaborbactam, demonstrated superior efficacy to piperacillin/tazobactam.
Cipro Not Better for UTI Prophylaxis After Transplant With Stent
April 30, 2017In a study of renal transplant patients who received ureteral stents, ciprofloxacin did not lower the incidence of UTI compared with SMX-TMP.
Guideline Confirmed for UTI in Children With Fever
December 02, 2016The researchers reaffirmed the 2011 UTI clinical practice guideline on infants and young children and reiterated the seven key action statements.
Meropenem-Vaborbactam Combo Noninferior for Complicated UTIs
November 03, 2016Meropenem-vaborbactam has the potential to be an important new drug in the treatment of patients with serious infections due to resistant organisms.
Cranberry Products Don't Prevent UTIs
November 02, 2016The researchers found no significant difference in the percent of women who had bacteriuria plus pyuria among those taking cranberry capsules or placebo.
Urine Concentration Helps Diagnose UTI in Infants
October 25, 2016The prevalence of UTI was 7.8% in infants tested for automated microscopic urinalysis.
Bacteremia in UTI Patients Tied to Abnormal CT Findings
October 04, 2016In a study of 189 adult UTI patients who underwent CT scans, investigators identified bacteremia in 40.2%.
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