Urinary Tract Infection

Abx-Resistant Enterobacteriaceae Tied to Clinical Failure in UTI

Abx-Resistant Enterobacteriaceae Tied to Clinical Failure in UTI

Poor clinical outcomes linked to extended spectrum cephalosporin-resistant Enterobacteriaceae.

PCR Test Bests Urine Cultures for UTI Pathogen Detection

PCR Test Bests Urine Cultures for UTI Pathogen Detection

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A multiplex polymerase chain reaction assay detected bacteria species missed by traditional urine culture as well as more fastidious bacteria.

Fluoroquinolones Tied to Increased Risk for Arrhythmia, CV Mortality

Fluoroquinolones Tied to Increased Risk for Arrhythmia, CV Mortality

To investigate the risk of cardiovascular adverse effects associated with this antibiotic class, researchers conducted a systematic review, meta-analysis, and network meta-analysis using studies identified through a search of MEDLINE, EMBASE, and the Cochrane Library.

In Complicated UTI, Cefiderocol Noninferior to Imipenem-Cilastin

In Complicated UTI, Cefiderocol Noninferior to Imipenem-Cilastin

Results from phase 2 study in patients with multidrug-resistant Gram-negative uropathogens.

UTI Risk After Urogynecologic Surgery Linked to Bladder Microbiome

UTI Risk After Urogynecologic Surgery Linked to Bladder Microbiome

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Depletion of Lactobacillus iners in the bladder appears to increase the risk of urinary tract infection following urogynecologic surgery, study finds.

Recurrent Cystitis Possibly Preventable by Drinking More Water

Recurrent Cystitis Possibly Preventable by Drinking More Water

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During a 12-month study, women who drank 1.5 L of water daily in addition to their usual fluid intake reduced their mean number of cystitis episodes nearly by half.

Zemdri Now Treats Complicated UTI, Pyelonephritis

Zemdri Now Treats Complicated UTI, Pyelonephritis

Zemdri carries a Boxed Warning describing reports of nephrotoxicity, ototoxicity, and neuromuscular blockade, as well as fetal harm if administered during pregnancy.

FDA Requires Safety Label Changes for Fluoroquinolones

FDA Requires Safety Label Changes for Fluoroquinolones

Changes will describe hypoglycemic coma and clarify and identify mental health side effects.

FDA Approves Drug for Complicated UTIs

FDA Approves Drug for Complicated UTIs

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Plazomicin, an aminoglycoside, was approved for treating complicated urinary tract infections in adults due to certain Enterobacteriaceae.

Prediction tool for urinary tract infections in preverbal children

1. The study reports the development of a clinical and biochemical prediction tool for assessing the risk of urinary tract infection in preverbal children with fever. The model developed accurately predicted which patients may need further testing based on clinical variables, and who may need antibiotics therapy based on urine analysis supplement. 2. In a []

Lower UTIs More Likely to Resolve With Nitrofurantoin Than Fosfomycin

Lower UTIs More Likely to Resolve With Nitrofurantoin Than Fosfomycin

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In a study of women with uncomplicated lower urinary tract infections, 70% of patients treated with nitrofurantoin had complete symptom resolution at 28 days vs 58% of those treated with fosfomycin.

UTI Calculator Predicts Risk of Infant Urinary Tract Infection

UTI Calculator Predicts Risk of Infant Urinary Tract Infection

Calculator reduces testing and decreases the number of urinary tract infections that were missed

Meropenem-vaborbactam non-inferior to piperacillin-tazobactam for complicated urinary tract infections: The TANGO I trial

1. In this randomized controlled trial, meropenem-vaborbactam was found to be non-inferior to piperacillin-tazobactam for treating complicated urinary tract infections (UTIs). 2. The rate of adverse events were similar between groups. Evidence Rating Level: 1 (Excellent) Study Rundown: As carbapenemases become more prevalent among organisms that cause complicated Urinary Tract Infections (UTIs), the need for []

Meropenem-vaborbactam Superior for Complicated UTIs

Meropenem-vaborbactam Superior for Complicated UTIs

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Overall treatment success occurred in 98.4% of patients receiving meropenem-vaborbactam vs 94% for those receiving piperacillin-tazobactam.

Post-Cystectomy UTI Risk Linked to Comorbidities

Post-Cystectomy UTI Risk Linked to Comorbidities

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A Charlson Comorbidity Index score of 2 or higher is an independent risk factor for urinary tract infections within 90 days following radical cystectomy for bladder cancer, study finds.

Sulfonamides, Nitrofurantoin Prescribed for UTI in Pregnant Women

Sulfonamides, Nitrofurantoin Prescribed for UTI in Pregnant Women

Nitrofurantoin, trimethoprim-sulfamethoxazole prescribed first trimester despite ACOG recs.

Confusion Tied to Antibiotics Rx in Nursing Home Residents With UTI

Confusion Tied to Antibiotics Rx in Nursing Home Residents With UTI

Confusion independently associated with receipt of antibiotics for UTI in nursing home residents.

Urinalysis Accurately Diagnoses UTIs in Febrile Infants

Urinalysis Accurately Diagnoses UTIs in Febrile Infants

Study shows test is sensitive and specific in infants younger than 60 days old.

Cyclists Have No Worse Sexual or Urinary Functions

Cyclists Have No Worse Sexual or Urinary Functions

No worse sexual or urinary function, but incidence of urethral stricture higher than swimmers/runners.

Bladder, Bowel Dysfunction More Likely in Girls vs Boys

Bladder, Bowel Dysfunction More Likely in Girls vs Boys

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New analysis finds that female sex and non-dilating vesicoureteral reflux are independently associated with an increased risk of bladder and bowel dysfunction.

NSAID vs Antibiotic for Symptomatic Urinary Tract Infection

NSAID vs Antibiotic for Symptomatic Urinary Tract Infection

Symptom resolution at day 3 was met by 54% in the diclofenac group vs 80% in the norfloxacin group.

Meat Often Contains Bacteria Linked to UTIs

Meat Often Contains Bacteria Linked to UTIs

Almost one-fourth of retail poultry contains E. coli strains associated with urinary tract infections

Recurrent UTIs Worsen Kidney Transplant Outcomes

Recurrent UTIs Worsen Kidney Transplant Outcomes

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Kidney transplant recipients who experience recurrent urinary tract infections are at increased risk of graft failure and death.

Drug Approved for Complicated Urinary Tract Infections

Drug Approved for Complicated Urinary Tract Infections

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Vabomere, which combines meropenem and vaborbactam, demonstrated superior efficacy to piperacillin/tazobactam.

Cipro Not Better for UTI Prophylaxis After Transplant With Stent

Cipro Not Better for UTI Prophylaxis After Transplant With Stent

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In a study of renal transplant patients who received ureteral stents, ciprofloxacin did not lower the incidence of UTI compared with SMX-TMP.

Guideline Confirmed for UTI in Children With Fever

Guideline Confirmed for UTI in Children With Fever

The researchers reaffirmed the 2011 UTI clinical practice guideline on infants and young children and reiterated the seven key action statements.

Meropenem-Vaborbactam Combo Noninferior for Complicated UTIs

Meropenem-Vaborbactam Combo Noninferior for Complicated UTIs

Meropenem-vaborbactam has the potential to be an important new drug in the treatment of patients with serious infections due to resistant organisms.

Cranberry Products Don't Prevent UTIs

Cranberry Products Don't Prevent UTIs

The researchers found no significant difference in the percent of women who had bacteriuria plus pyuria among those taking cranberry capsules or placebo.

Urine Concentration Helps Diagnose UTI in Infants

Urine Concentration Helps Diagnose UTI in Infants

The prevalence of UTI was 7.8% in infants tested for automated microscopic urinalysis.

Bacteremia in UTI Patients Tied to Abnormal CT Findings

Bacteremia in UTI Patients Tied to Abnormal CT Findings

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In a study of 189 adult UTI patients who underwent CT scans, investigators identified bacteremia in 40.2%.

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