Well-Being of Young Adults on Kidney Replacement Tx Studied

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Well-being and medication adherence negatively linked to psychological morbidity, dialysis.
Well-being and medication adherence negatively linked to psychological morbidity, dialysis.

(HealthDay News) -- For young adults receiving kidney replacement therapy (KRT), well-being and medication adherence are associated with psychological morbidity, according to a study published online in the Clinical Journal of the American Society of Nephrology.

Alexander J. Hamilton, MD, from the University of Bristol in the United Kingdom, and colleagues conducted an online survey for young adults receiving KRT. Outcomes were compared by treatment modality using age- and sex-adjusted regression models. They examined the correlation between psychosocial associations with scores on the Warwick-Edinburgh Mental Wellbeing Scale and the eight-item Morisky Medication Adherence Scale.

A total of 976 young adults were recruited, and 64 percent of them responded to the survey, including 417 with transplants and 173 on dialysis. The researchers observed a positive association for well-being with extraversion, openness, independence, and social support; negative associations were identified with neuroticism, negative body image, stigma, psychological morbidity, and dialysis. There were correlations for higher medication adherence with living with parents, conscientiousness, physician access satisfaction, patient activation, age, and male sex; lower adherence was seen to be associated with comorbidity, dialysis, education, ethnicity, and psychological morbidity.

"Our results suggest a possible role for routine measurement of psychological health in young people, to avoid missing opportunities to identify and improve mental health," the authors write. "This could help identify those at higher risk of poor outcomes for close monitoring, greater psychosocial support, or targeted interventions."

References

Hamilton AJ, Caskey FJ, Casula A, Inward CD, and Ben-Shlomo Y. Associations with Wellbeing and Medication Adherence in Young Adults Receiving Kidney Replacement Therapy. Clin J Am Soc Nephrol. October 2018, CJN.02450218; DOI:10.2215/CJN.02450218

Duquette P and Helm K. Treatment Adherence in Young Adults Receiving Kidney Replacement Therapy: A Caregiver Perspective. Clin J Am Soc Nephrol. October 2018, CJN.11200918; DOI:10.2215/CJN.11200918

Grandinetti A. Treatment Adherence in Young Adults Receiving Kidney Replacement Therapy: A Patient Perspective. Clin J Am Soc Nephrol. October 2018, CJN.11230918; DOI:10.2215/CJN.11230918

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