Transplantation

Considerations for Transplants From People With HCV to Those Without

Considerations for Transplants From People With HCV to Those Without

The use of direct-acting antiviral agents to treat chronic HCV could allow for transplantation from donors HCV to recipients without the disease.

Procurement Biopsy of Deceased Donor Kidneys Poorly Reproduced

Procurement Biopsy of Deceased Donor Kidneys Poorly Reproduced

Also do not correlate well with reperfusion biopsies, not linked to transplant outcomes

Kidneys Transplanted in France Would Be Discarded in US

Kidneys Transplanted in France Would Be Discarded in US

Donor profile index of transplanted kidneys has risen modestly in US, with greater increase in France.

High Gout Burden Found Among Solid Organ Transplant Recipients

High Gout Burden Found Among Solid Organ Transplant Recipients

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Study reveals an 11% prevalence of active gout among solid organ transplant recipients overall and a 13% prevalence among kidney transplant recipients.

Obesity Should Not Rule Out Kidney Transplantation

Obesity Should Not Rule Out Kidney Transplantation

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In a study, kidney transplant recipients with a BMI (in kg/m2) higher than 35 have graft and patient outcomes similar to those with a BMI of 30 to 35.

Pre-Transplant Weight Loss Predicts Higher Post-Transplant Death Risk

Pre-Transplant Weight Loss Predicts Higher Post-Transplant Death Risk

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Patients who lose 10% or more of their body weight from the time of their listing on a transplant waiting list are at higher risk of death following deceased-donor kidney transplantation.

High-Dose Influenza Vaccination May Benefit Transplant Recipients

High-Dose Influenza Vaccination May Benefit Transplant Recipients

Double-dose influenza vaccine is safe and may increase antibody response in solid-organ transplant recipients

Well-Being of Young Adults on Kidney Replacement Tx Studied

Well-Being of Young Adults on Kidney Replacement Tx Studied

Well-being and medication adherence negatively linked to psychological morbidity, dialysis.

Less Pre-Kidney Transplant Dialysis With Preemptive Waitlist

Less Pre-Kidney Transplant Dialysis With Preemptive Waitlist

Preemptively listed recipients have about four fewer years of pretransplant dialysis

Kidney Transplant Outcomes Unaffected by Dialysis Modality

Kidney Transplant Outcomes Unaffected by Dialysis Modality

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Patient and graft survival are similar for patients who were on hemodialysis and peritoneal dialysis prior to transplantation.

Kidney Donor Candidates May Have Various Incidentally Detected Lesions

Kidney Donor Candidates May Have Various Incidentally Detected Lesions

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Potential donors undergoing multidetector computed tomography during their assessment should be counseled on the medical implications of incidentally discovered lesions.

Using HCV-infected kidneys greatly reduces wait time for transplantation and improves survival for patients with HCV

1. Use of HCV-infected kidneys increased patients' quality-adjusted life expectancy. 2. Lower costs were associated with HCV-infected kidneys compared to transplanting HCV-uninfected kidneys to HCV-positive patients. Evidence Rating Level: 2 (Good) Study Rundown: Organ availability for transplantation is limited; therefore, for patients with end stage renal disease (ESRD), hemodialysis is often the final treatment compared []

Good Outcomes for HCV-Negative Recipients of HCV Kidneys

Good Outcomes for HCV-Negative Recipients of HCV Kidneys

All 20 recipients experienced HCV cure, good quality of life, excellent renal function.

Progress in Graft Survival Has Slowed

Progress in Graft Survival Has Slowed

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After 2000, investigators observed a deceleration in short-term improvements in graft survival.

Patient Social Support Influential Factor for Transplant Providers

Patient Social Support Influential Factor for Transplant Providers

Recipient social support most influential factor for providers concerned with avoiding organ wastage.

HCV-Infected Kidney Transplant More Efficient in HCV-Infected

HCV-Infected Kidney Transplant More Efficient in HCV-Infected

Increases quality-adjusted life expectancy, reduces costs versus transplant of HCV-uninfected kidney.

Medicaid Expansion Ups Preemptive Listing for Kidney Transplant

Medicaid Expansion Ups Preemptive Listing for Kidney Transplant

From pre- to post-expansion period, 59% relative increase in Medicaid-covered preemptive listings.

Pediatric Kidney Recipients Often Have Subclinical Inflammation

Pediatric Kidney Recipients Often Have Subclinical Inflammation

Associated with increased risk of composite end point of acute rejection, allograft failure.

Sun Defenses Up in Transplant Patients After Skin Cancer Study

Sun Defenses Up in Transplant Patients After Skin Cancer Study

Increased odds of using multiple sun protection measures among organ transplant recipients.

Post-Transplant Tx Reduces Wait for Kidney in Hep C+ Patients

Post-Transplant Tx Reduces Wait for Kidney in Hep C+ Patients

Delaying treatment until after transplant doesn't adversely impact kidney allograft or survival.

Remaining Kidney Health Most Important Concern for Donors

Remaining Kidney Health Most Important Concern for Donors

Other concerns expressed by living donors include surgical, lifestyle, psychosocial impact of donation.

Proportion of Drug-Intoxicated Organ Donors on the Rise in US

Proportion of Drug-Intoxicated Organ Donors on the Rise in US

No difference in survival between recipients of organs from drug-intoxicated donors, other donors.

Bladder Cancer, UTUC More Common in Kidney Transplant Recipients

Bladder Cancer, UTUC More Common in Kidney Transplant Recipients

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A study found that bladder cancer and UTUC occurred in 122.22 and 113.97 per 100,000 persons per year, respectively, among kidney transplant recipients.

Liver-Kidney Recipients Have Donor-Specific Hypo-Responses

Liver-Kidney Recipients Have Donor-Specific Hypo-Responses

Unique characteristics ID'd in peripheral blood cells of simultaneous liver-kidney transplant recipients.

Optimizing organ donations from overdose deaths may help address national organ shortage

1. U.S. transplants using organs from overdose-death donors (ODDs) has increased 24-fold from 2000 to 2016, and transplant outcomes from organs donated by ODDs have been noninferior to those donated by trauma-death donors (TDDs) and medical-death donors (MDDs). 2. Compared to TDD organs, ODD kidneys and livers were discarded at a greater rate. Evidence Rating []

Organ Transplants Involving Overdose-Death Donors Increasing

Organ Transplants Involving Overdose-Death Donors Increasing

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The number of transplants in the United States involving organs from individuals who died from a drug overdose rose from 149 in 2000 to 3533 in 2016.

Many Providers Unaware of Racial Disparities in Kidney Transplants

Many Providers Unaware of Racial Disparities in Kidney Transplants

Nurse managers, white providers more likely to be unaware of national racial disparity in waitlisting

Renal Allograft Failure Linked to Low Uromodulin Levels

Renal Allograft Failure Linked to Low Uromodulin Levels

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Kidney transplant recipients in the highest tertile of serum uromodulin concentration had a 2-fold increased risk of allograft failure compared with those in the lowest tertile.

Large Drop Seen in Infection-Related Post-Transplant Deaths

Large Drop Seen in Infection-Related Post-Transplant Deaths

Findings among adults undergoing kidney transplantation in Finland 1990 to 2010

Organ Donation Decision Not Linked to Family Grief

Organ Donation Decision Not Linked to Family Grief

Families making decision not to donate relative's organs experience lower quality communication

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