Managing Anemia in CKD: Beyond Iron and ESAs
Iron therapy and erythropoiesis-stimulating agents are not always effective for anemia in patients with CKD. Nutritional interventions may be helpful in these cases.
Diagnosis & Disease Information
Nicotinamide Does Not Prevent Keratinocyte Cancers in Organ Recipients
No difference seen in keratinocyte cancers or actinic keratoses for organ-transplant recipients receiving oral nicotinamide or placebo
Vitamin D Supplementation Less Effective With Higher BMI
Further, baseline vitamin D-related biomarkers lower for individuals with higher BMI
Higher Vitamin D Levels Correlate With Lower PTH in CKD Population
The 2017 KDIGO guideline for CKD-MBD may be too conservative, according to investigators.
Excessive Body Weight Lessens the Efficacy of Vitamin D Supplements
A round up of studies suggests it is difficult to increase serum total 25-hydroxyvitamin D levels enough to effectively lower elevated parathyroid hormone (PTH) levels in overweight patients with chronic kidney disease.
Folate Deficiency in Seniors May Increase Dementia, Mortality Risks
But evidence suggests that reverse causation may play a role in the links between serum folate deficiency and dementia, all-cause mortality
Cholecalciferol Beneficial for Bone Loss in Kidney Transplant Recipients
The effect of cholecalciferol supplementation on parathyroid hormone levels and bone loss at the lumbar spine in kidney transplant recipients was studied in a placebo-controlled trial.
Low Selenium Levels Linked With Poor Response to ESAs in Hemodialysis
Previous studies indicate that selenium and selenoproteins are involved in erythropoiesis.
Marine Omega-3 Supplements Tied to Higher Atrial Fibrillation Risk
Risk appeared to be greater in trials testing >1 g/day dosing
Vitamin D Does Not Impact Kidney Outcomes in Prediabetes
Secondary analysis of randomized trial shows no difference in progression of KDIGO risk scores with daily vitamin D versus placebo
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