Algorithm Predicts Urinary Tract Infection Without Microscopy
Authors say the new algorithm could be used to safely withhold antibiotics in low-risk patients in the primary care setting
Diagnosis & Disease Information
Trimethoprim-Sulfamethoxazole vs Amoxicillin Ups Hyperkalemia Risk
Trimethoprim-sulfamethoxazole is mostly excreted through the kidneys, and it can cause hyperkalemia by reducing potassium excretion.
Antibiotic Prophylaxis Guidelines for Radical Cystectomy Often Not Followed
Only 27% of patients undergoing radical cystectomy with ileal conduit received antibiotic prophylaxis according to AUA guidelines, a study found.
Cefepime-Enmetazobactam Treats Complicated UTI, Acute Pyelonephritis
Cefepime-enmetazobactam may be more effective than piperacillin-tazobactam in treating complicated UTI and acute pyelonephritis caused by organisms that produce extended-spectrum β-lactamases (ESBL), investigators suggested.
Kidney Stone Disease, Urinary Tract Infection ‘Mutually Coexisting’
Review authors concluded that urinary tract infection and kidney stone disease are “reciprocally causal.”
Inappropriate Antibiotic Prescribing for Uncomplicated Cystitis Still Occurs
Urologists appear more likely than other specialists to inappropriately treat uncomplicated cystitis, according to study findings.
AKI-to-CKD Transition Predicts Higher Infection Risk
Following an episode of acute kidney injury, patients who transition to chronic kidney disease have a significant 1.5-fold increased long-term risk for infection, a study found.
Higher Fluoroquinolone Doses May Be Toxic in Advanced CKD
Guidelines recommend that clinicians prescribe fluoroquinolone at lower doses in patients with reduced kidney function.
FDA Needs More Data on Tebipenem HBr for Complicated UTI
In the CRL, the FDA stated that the application could not be approved in its present form and that an additional clinical trial would be required.
Endometrial Cancer Ups Risks for UTI, Kidney Failure
The increased risk for several urinary tract problems among women diagnosed with endometrial cancer varies by age and race or ethnicity, a study found.
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