In a study, IV fosfomycin appeared less effective than IV ceftriaxone or meropenem for bacteremic UTI caused by multidrug-resistant E. coli, but the drug may be considered for selected patients with these infections, according to investigators.
Researchers conducted a study to assess the safety and efficacy of aminoglycosides or polymyxin monotherapy for the treatment of adults with complicated urinary tract infections caused by extensively drug-resistant Pseudomonas aeruginosa.
The application includes data from the phase 3 ADAPT-PO trial, which evaluated the efficacy and safety of tebipenem HBr in 868 adults with cUTI or acute pyelonephritis.
Study finds that among women with uncomplicated urinary tract infection (UTI), those with antimicrobial-resistant isolates are at increased risk for progression to complicated UTI vs those with susceptible isolates.
Researchers conducted a crossover study to determine whether probenecid and cephalexin administered together increases the clinical benefits of cephalexin.
Investigators conducted a cohort study that compared adverse effects and outcomes among patients with community-acquired urinary tract infection treated with cotrimoxazole vs fluoroquinolones.
The American College of Physicians convened a panel to identify best practices for the use of short-course antibiotics in the management of common infections.
More severe frailty predicted a higher risk of UTIs.
Clinical case: A healthy 25-year-old woman is referred for recurrent urinary tract infections (rUTI).
Findings support prescribing antimicrobials for no longer than needed.
