Benefit-Risk Considerations of Cefiderocol in Clinical Practice
Study authors discuss the uncertainties and challenges in the interpretation of the CREDIBLE-CR trial and benefit-risk considerations for the use of cefiderocol in clinical practice.
Urinary Tract Infection
Tool Could Optimize Antibiotic Prescribing for UTI
Researchers tested a new decision support tool to optimize antibiotic prescribing for uncomplicated urinary tract infection.
Oral β-lactam Antibiotics Are a Reasonable Step-Down Rx for Bacteremia
Study findings suggest that oral β-lactam antibiotics as step-down treatment following treatment with parenteral antibiotics may treat bacteremia from a urinary source when fluoroquinolones or trimethoprim-sulfamethoxazole use is limited by adverse effects or resistance.
Intravesical Phage Therapy May Treat UTI in Men Undergoing TURP
Research authors assessed the safety and efficacy of intravesical bacteriophage therapy compared to placebo and current standard of care for the treatment of urinary tract infection in patients undergoing transurethral resection of the prostate.
Some Patients Have Increase in Cardiac Events With Azithromycin
Risk for cardiac events higher with azithromycin versus amoxicillin in those using QT-prolonging drugs.
Hospital Admissions Not Related to COVID-19 Fell in Early 2020
From February to April 2020, drop >20% observed for all primary admission diagnoses.
Risk of Cardiac Events With Azithromycin, Amoxicillin Compared
The aim of the study was to use real-world data to compare the risk of cardiac events in new users of azithromycin vs amoxicillin.
Risk of Aortic Aneurysm, Dissection With Fluoroquinolones Examined
The observational study aimed to determine the association between fluoroquinolone use and the risk of aortic aneurysm or aortic dissection while taking into account potential confounding.
Protocolized Urine Sampling Reduces Catheter-Associated UTI
Investigators sought to determine whether a new protocol for urine sampling and testing lowers rates of catheter-associated urinary tract infections.
Menopausal Hormonal Therapy May Cut UTI Risk
New study is the first focused analysis of bacterial diversity in the urogenital tract of postmenopausal women, according to investigators.
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