Time to Metastasis May Be a Surrogate for UTUC Survival After Surgery
In a study, distant metastasis emerged as the best candidate to be a surrogate end point for survival among patients receiving surgical treatment for UTUC.
Diagnosis & Disease Information
Segmental Ureterectomy Appears Non-Inferior to RNU in UTUC
Segmental ureterectomy is increasingly adopted for high-risk upper tract urothelial carcinoma.
Current Smoking in UTUC Cases Predicts Post-RNU Disease Recurrence
A recent study characterized disease recurrence patterns and predictive risk factors for recurrence in patients who underwent radical nephroureterectomy for low-grade upper tract urothelial carcinoma.
Kidney-Sparing Surgery Offers Effective Oncologic Control in High-Risk UTUC
In this small study, even patients with high-risk tumors appeared to benefit from nephron-sparing surgery.
Older Adults May Benefit From NAC Prior to UTUC Radical Surgery
Neoadjuvant chemotherapy prior to radical nephroureterectomy for upper tract urothelial carcinoma may improve pathologic outcomes regardless of age, new data suggest.
Epigenetic Test May Rule Out High-Grade UTUC
If validated, the EpiCheck® assay may identify more patients who can safely delay or avoid nephroureterectomy.
Metastasectomy for Metastatic Urothelial Cancer Does Not Improve Survival
A study showed that 2- and 5-year overall survival rates did not differ significantly between patients who underwent metastasectomy and those who did not.
Adjuvant Nivolumab Improves Outcomes in High-Risk Urothelial Carcinoma
Nivolumab treatment for patients who have undergone radical surgery for high-risk muscle-invasive urothelial carcinoma improves their disease-free survival compared with placebo, a study shows.
Ureteroscopic Biopsy in UTUC May Increase Risk of Intravesical Recurrence
Compared with no ureteroscopy or percutaneous biopsy, ureteroscopic biopsy in patients with upper tract urothelial carcinoma was significantly associated with a 40% increased risk for intravesical recurrence of disease.
Prophylactic Ureteral Stenting Linked to Upper Tract Urothelial Carcinoma
In current urological practice, clinicians decide whether to place a ureteral stent or nephrostomy, but evidence-based treatment guidance is needed.
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