Kidney-Sparing Surgery Offers Effective Oncologic Control in High-Risk UTUC
In this small study, even patients with high-risk tumors appeared to benefit from nephron-sparing surgery.
Upper Tract Urothelial Carcinoma
Older Adults May Benefit From NAC Prior to UTUC Radical Surgery
Neoadjuvant chemotherapy prior to radical nephroureterectomy for upper tract urothelial carcinoma may improve pathologic outcomes regardless of age, new data suggest.
Epigenetic Test May Rule Out High-Grade UTUC
If validated, the EpiCheck® assay may identify more patients who can safely delay or avoid nephroureterectomy.
Metastasectomy for Metastatic Urothelial Cancer Does Not Improve Survival
A study showed that 2- and 5-year overall survival rates did not differ significantly between patients who underwent metastasectomy and those who did not.
Adjuvant Nivolumab Improves Outcomes in High-Risk Urothelial Carcinoma
Nivolumab treatment for patients who have undergone radical surgery for high-risk muscle-invasive urothelial carcinoma improves their disease-free survival compared with placebo, a study shows.
Ureteroscopic Biopsy in UTUC May Increase Risk of Intravesical Recurrence
Compared with no ureteroscopy or percutaneous biopsy, ureteroscopic biopsy in patients with upper tract urothelial carcinoma was significantly associated with a 40% increased risk for intravesical recurrence of disease.
Prophylactic Ureteral Stenting Linked to Upper Tract Urothelial Carcinoma
In current urological practice, clinicians decide whether to place a ureteral stent or nephrostomy, but evidence-based treatment guidance is needed.
Radiation Therapy Increases Survival in Metastatic Urothelial Carcinoma
Patients with metastatic urothelial carcinoma have significantly longer overall survival when treated with a combination of radiotherapy and chemotherapy compared with chemotherapy alone, a study found.
Bone Metastases Predict Worse mUC Immunotherapy Outcomes
The presence of bone metastases is associated with shorter survival among patients who received single-agent immunotherapy for metastatic urothelial carcinoma.
Cytoreductive Surgery May Have a Role in Treating Metastatic UTUC
A study of patients with metastatic upper tract urothelial carcinoma demonstrated that those who underwent cytoreductive surgery after chemotherapy had significantly improved survival compared with those who received chemotherapy alone.
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