Estimating Post-Nephrectomy GFR May Guide Treatment Decisions
An accurate estimate of future GFR after nephrectomy would help to guide operative strategy and use of adjuvant or neoadjuvant therapies, according to a recent editorial.
Upper Tract Urothelial Carcinoma
UTUC Adjuvant Chemotherapy Beneficial in Selected Cases
Adjuvant chemotherapy prolongs survival among patients with negative surgical margins regardless of number of positive lymph nodes.
Predictors of Recurrence After RNU for Low-Grade UTUC
Findings may inform surveillance strategies and improve treatment outcomes.
UTUC in Octogenarians Frequently Managed Without Surgery
Approximately one-quarter of patients aged 80 years or older with upper tract urothelial carcinoma are managed expectantly, data show.
Time to Metastasis May Be a Surrogate for UTUC Survival After Surgery
In a study, distant metastasis emerged as the best candidate to be a surrogate end point for survival among patients receiving surgical treatment for UTUC.
Segmental Ureterectomy Appears Non-Inferior to RNU in UTUC
Segmental ureterectomy is increasingly adopted for high-risk upper tract urothelial carcinoma.
Current Smoking in UTUC Cases Predicts Post-RNU Disease Recurrence
A recent study characterized disease recurrence patterns and predictive risk factors for recurrence in patients who underwent radical nephroureterectomy for low-grade upper tract urothelial carcinoma.
Kidney-Sparing Surgery Offers Effective Oncologic Control in High-Risk UTUC
In this small study, even patients with high-risk tumors appeared to benefit from nephron-sparing surgery.
Older Adults May Benefit From NAC Prior to UTUC Radical Surgery
Neoadjuvant chemotherapy prior to radical nephroureterectomy for upper tract urothelial carcinoma may improve pathologic outcomes regardless of age, new data suggest.
Epigenetic Test May Rule Out High-Grade UTUC
If validated, the EpiCheck® assay may identify more patients who can safely delay or avoid nephroureterectomy.
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