Uric Acid May Predict Graft Survival
SAN FRANCISCO—Increased uric acid levels early after kidney transplantation are associated with worse graft survival, data show.
Transplantation
Positive Crossmatch Need Not Stop Tx
SAN FRANCISCO—Many renal transplant candidates who have a positive AHG-CDC crossmatch can undergo successful transplantation, a new study suggests. The study showed that only 41% of recipients with weak AHG-CDC positive crossmatches have HLA-specific donor-specific antibody (DSA).
Drug May Reduce Proteinuria
SAN FRANCISCO—A new study found that converting from tacrolimus/sirolimus (TAC/SRL) to TAC/enteric-coated mycophenolic sodium (EC-MPS) may reduce proteinuria in renal transplant patients.
New Transplant Rules Issued
New regulations for organ transplantation issued by the Centers for Medicare Medicaid Services (CMS) emphasize survival rates and protecting the rights of living donors.
Transplant Outpatients Often Subject to Drug Errors
Medication mistakes are common among patients who have received liver, kidney or pancreas transplants, researchers at the Yale University School of Medicine reported recently.
Hypertension in Renal Tx Recipients
Hypertension is a common clinical problem in renal transplant patients, and it has important consequences for patient and graft survival. At five years after transplantation, more than 50% of patients have Stage I or Stage II hypertension and nearly 40% of patients have prehypertension.
Gallstone Disease in Renal Transplant Patients Defined
The incidence of gallstone disease in patients on a kidney transplantation waiting list is similar to that of the general population, but in transplant patients, the complications may be severe, researchers in Finland report. They recommend screening and treatment of pre- and post-transplantation gallstone disease.
Post-Tx Diabetes Risks Characterized
Risk factors for new-onset diabetes after renal transplantation include tacrolimus immunosuppression and older age and heavier weight at the time of transplantation.
Post-Tx Infection Risks Identified
Younger age, female gender, and antibody induction are among the risk factors for infection-related hospitalizations following renal transplantation, according to two studies.
Pediatric Kidneys Prove Viable Transplants
SAN DIEGO—En-bloc transplants of kidneys from infants and young children into adult recipients may offer better outcomes than deceased expanded criteria donor (ECD) organs, data show.
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