Prophylactic Regimen Probed as Strategy to Transplant HCV-Infected Kidneys
Among respondents to a 2019 survey of US transplant program staff, 42% reported that they do not accept HCV-viremic kidneys for uninfected transplant candidates.
Transplantation
Return-to-School Recommendations Issued for Organ Transplant Recipients
Shared decision-making recommended for solid organ transplant recipient families, professionals.
HIV+ Donor to HIV+ Recipient Feasible for Kidney Transplant
Outcomes similar for HIV+, HIV− donors; trend toward higher rejection found for HIV+ donors.
Avacopan NDA Submitted for ANCA-Associated Vasculitis
ChemoCentryx, Inc has submitted a NDA to the Food and Drug Administration (FDA) for acavopan in the treatment of antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis.
COVID-19 Outcomes in Kidney Failure Cases Described
In separate COVID-19 studies, investigators found that only some infected kidney transplant outpatients required hospitalization and patients on maintenance hemodialysis often have an atypical presentation of symptoms.
Updated Guidance Provided for Safe Solid Organ Transplantation
Universal donor nucleic acid testing for HIV, HBV, HCV and post-transplant monitoring recommended.
CDC: Transplant, CKD Patients at High Risk for Severe COVID-19 Illness
Many patients with kidney disease are at high risk for severe COVID-19 illness, according to a CDC update.
Proton Pump Inhibitors May Up Death Risk in Kidney Transplant Recipients
In a study of kidney transplant recipients, PPI users had an almost 2-fold increased risk of mortality compared with nonusers.
Living Kidney Donors Face Elevated Risk of Ischemic Heart Disease
A study of 1029 living kidney donors in Norway found that they had significant 64% increased odds of ischemic heart disease compared with health controls.
Potassium Binders Appear Effective for Hyperkalemia in Transplant Recipients
In 2 small case series of solid-organ transplant recipients, the potassium binders patiromer and sodium zirconium cyclosilicate appeared effective in the short term in managing hyperkalemia.
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