A new meta-analysis found that cinacalcet plus vitamin D combination therapy and vitamin D monotherapy have similar effects on parathyroid hormone levels in dialysis patients with secondary hyperparathyroidism.
For patients on peritoneal dialysis, 1.75 vs 1.25 mmol/L dialysate calcium was superior at reducing intact parathyroid hormone levels, meta-analysis revealed.
In a small study, hungry bone syndrome developed in nearly 29% of patients despite receiving high-dose calcitriol prior to total parathyroidectomy with autotransplantation.
A new review suggests transitioning from a disease-oriented approach to a patient-oriented approach for better risk-benefit balance.
Hungry bone syndrome developed in nearly 88% of patients following parathyroidectomy with autotransplantation for refractory secondary hyperthyroidism.
In a study of CKD patients, patients with baseline PTH levels of 0, 69, and 58 pg/mL had the lowest risks for fracture, vascular events, and death, respectively.
In a study of hemodialysis patients, pre-operative potassium higher than 3.9 mmol/L correlated with greater risk for hyperkalemia after parathyroidectomy.
In a small study, 34% of dialysis patients had vertebral fractures, and patients in the highest tertile of parathyroid hormone level had a nearly 3-fold increased risk of these fractures compared with those in the middle tertile.
New data support aggressive vitamin D repletion to a revised serum 25-hydroxyvitamin D target of at least 51 ng/mL in patients with chronic kidney disease.
Twice as many patients taking a high cinacalcet dose before transplantation required subsequent parathyroidectomy persistent secondary hyperparathyroidism.
