Parathyroidectomy Ups Cardiovascular Risks in Dialysis Patients
Dialysis patients who underwent parathyroidectomy had a 24% greater risk for cardio- and cerebrovascular events than similar patients who did not undergo the surgery.
Secondary Hyperparathyroidism
Study: Etelcalcetide Can Be Used Safely by Registered Dietitians, Nurses
In a study, hypocalcemia and gastrointestinal adverse events were managed through etelcalcetide dose modification or discontinuation.
Vitamin D and iPTH Levels Vary by Season
In a large study of dialysis patients, serum 25-hydroxyvitamin D levels peaked in summer and declined in winter.
Oral Evocalcet Appears Effective for SHPT
In 2 small trials of Japanese patients with SHPT on dialysis, evocalcet treatment reduced iPTH to target levels in a majority of patients within 30 to 32 weeks.
TPTx Plus Autotransplantation May Provide Better Long-Term PTH Control
At 6 months after surgery, just 6.7% TPTx + AT had parathyroid hormone levels exceeding 200 pg/mL, compared with 38.9% of SPTx patients
Vitamin K Antagonists, Liver Dysfunction Implicated in Calciphylaxis
In a small study, vitamin K antagonist use and liver dysfunction emerged as the most important factors in the development of calciphylaxis.
Target Vitamin D Levels in CKD With SHPT May Need Updating
In an analysis of 2 randomized trials of patients with stage 3 to 4 chronic kidney disease, iPTH suppression did not occur until serum 25-hydroxyvitamin D rose to at least 50.8 ng/mL.
Post-Parathyroidectomy Hungry Bone Syndrome Less Problematic in PD
In a single center study, hungry bone syndrome developed in fewer patients on peritoneal dialysis than hemodialysis after parathyroidectomy.
Pretransplantation PTH May Influence the Risk for Tertiary HPT
In a study, patients with the highest preoperative levels of PTH tended to have higher postoperative levels than other transplant recipients.
SHPT Linked With Low Bone Density in CKD
In a study of patients with chronic kidney disease, secondary hyperparathyroidism was associated with high risk for reduced bone mineral density, particularly at the hip.
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