Adjuvant Radiation May Provide a Survival Benefit Over Salvage Radiation in High-Risk Prostate Cancer
Low-risk patients did not appear to benefit from adjuvant radiation.
Radiotherapy
Prostate Cancer Survival Rates Vary by Gleason Grade Group 5 Pattern
Biopsy Gleason patterns 4+5, 5+4, and 5+5 should be given separate consideration in pretreatment risk stratification, according to investigators.
Prostate Radiation Therapy Tied to Improved Survival in Newly-Diagnosed mHSPC
Radiation therapy directed at the primary prostate tumor decreased mortality risk by 31% in adjusted analyses, a study found.
Ultra-High Single-Dose Radiation Therapy Tested for Prostate Cancer
In a small phase 2 trial involving men with intermediate-risk prostate cancer, a single ultra-high dose of radiation was safe and comparable to curative hypofractionated stereotactic body radiation therapy in tumor control and quality-of-life measures.
Model Proposed to Guide Use of Adjuvant Radiation Therapy for MIBC
Investigators found that the odds of locoregional recurrence of muscle-invasive bladder cancer following radical cystectomy depend on disease risk category.
Prostate Cancer Bone Metastasis Burden Tied to Prostate RT Survival Benefit
The overall and failure-free survival benefit of adding prostate radiation therapy to standard of care for metastatic prostate cancer declines with increasing number of bone metastases, a study found.
Localized PCa Therapies Safely Delivered During COVID-19 Peak at NYC Center
A cancer center in New York City safely managed patients with localized prostate cancer during the height of the COVID-19 pandemic in 2020, providing insights for handling a second COVID-19 wave.
Optimal Sequencing of ADT and RT for Low PSA Prostate Cancer Probed
During the COVID-19 pandemic, neoadjuvant ADT has been used as a way to delay initiation of daily radiation therapy, but it may not be appropriate for all men.
Whole-Pelvic vs Prostate-Only RT Better for High-Risk Prostate Cancer
A randomized phase 3 trial demonstrated that whole-pelvic radiation therapy was associated with improved biochemical failure-free and disease-free survival compared with prostate-only radiation in patients with high-risk and very high-risk prostate cancer.
Salvage Therapies for Radiorecurrent Prostate Cancer Offer Similar RFS
Surgical and nonsurgical local salvage treatments for prostate cancer (PCa) that recurs following radiation therapy offer similar 5-year recurrence-free survival (RFS) rates, but re-irradiation appears to result in less toxicity, according to a new meta-analysis. A team led by Amar U. Kishan, MD, of the University of California, Los Angeles, analyzed data from 150 studies…
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