Biochemical Recurrence Risk Differs by Prostate Cancer Zone
Finding is based on a meta-analysis of 14 high-quality studies involving 19,365 patients.
Finding is based on a meta-analysis of 14 high-quality studies involving 19,365 patients.
Study findings suggest that chemoradiation therapy could be considered an alternative to surgery in this patient population.
Nevertheless, thorough extended pelvic lymph node dissection cannot be omitted, investigators cautioned.
Risk for all-cause mortality up for men receiving post-radical prostatectomy salvage radiation therapy at PSA level >0.25 ng/mL
Most men with localized prostate cancer do not die within 15 years, whether or not they receive active surveillance or treatment.
New findings could have implications for the use of salvage therapies.
Investigators analyzed data from 3 randomized controlled trials and data from their own prospective institutional database.
Cytoreductive radical prostatectomy for newly diagnosed metastatic hormone-sensitive prostate cancer can be performed with minimal morbidity and is associated with a low risk for symptomatic local recurrence.
As far as investigators are aware, their study is the first randomized controlled trial comparing radical prostatectomy and stereotactic body radiation therapy.
The finding emerged from a propensity-score matched analysis of 1058 men who underwent robot-assisted radical prostatectomy for prostate cancer.