Canagliflozin Ups Survival in Type 2 Diabetes With Macroalbuminuria
Canagliflozin vs placebo is associated with increased survival and renal outcomes in patients with type 2 diabetes and macroalbuminuria.
Proteinuria
Lixisenatide Cuts Kidney Damage in T2DM and Coronary Syndrome
Lixisenatide reduces progression of urinary albumin-creatinine ratio in patients with macroalbuminuria.
Novel Signal ID’d for Microalbuminuria in Europeans With T2DM
Genome-wide association study identified novel signal near GABRR1, which was not seen in Asians.
Kidney Failure Associated With Low Albumin Levels
End-stage renal disease is more likely to develop in individuals with serum albumin levels of 4.1 g/dL or below than in those with levels of 4.4 g/dL or higher.
Most Type 1 Diabetes Patients Have Kidney Disease
Incidence of end-stage renal disease has declined but affects substantial portion of long-term T1D patients.
Albuminuria Associated With Cognitive Impairment, Dementia
The researchers found that albuminuria correlated with cognitive impairment, dementia, clinical Alzheimer’s disease, and vascular dementia.
Pre-dialysis CKD Is a Risk Factor for Serious Infection
Lower eGFR and higher ACR are associated with an elevated risk of infection-related hospitalization and infection-related death.
Sodium Reduction May Improve Albuminuria in Nondiabetic CKD
Reducing sodium consumption to about 2,500 mg daily was associated with albuminuria improvement.
Liraglutide Found to Reduce Albuminuria in Diabetes Patients
Use of the glucagon-like peptide-1 receptor agonist lowered 24-hour urinary albumin excretion rate by 32% over 12 weeks versus placebo.
Saxagliptin Linked to Albuminuria Improvement
Treatment with saxagliptin was associated with improvement in ACR categories for individuals with normoalbuminuria, microalbuminuria, and macroalbuminuria.
