Belimumab Shows Efficacy in Real-World Lupus Nephritis Population
Renal response at 6 months strongly predicted belimumab’s durability.
Proteinuria
Finerenone Provides CV, Renal Benefits in Diabetes Across CKD Spectrum
In FIDELITY, investigators pooled data from more than 13,000 patients from the FIDELIO-DKD and FIGARO-DKD trials.
Combination of eGFR and UACR Better Predicts CKD Progression
Using changes in UACR and eGFR as an alternative outcome for kidney failure in trials of CKD progression warrants further evaluation, according to investigators.
Primary Nephrotic Syndrome Increases ESKD, Cardiovascular Risks
Among the study findings, primary nephrotic syndrome was associated with an excess risk of heart failure hospitalization.
CKD May Be Underdiagnosed in ‘Lower Risk’ Groups
In a study of military health system beneficiaries, patients with uncoded CKD had fewer proteinuria, serum creatinine, and eGFR results, suggesting kidney function and damage was not monitored closely.
Semaglutide Effective in High-Risk Diabetic Kidney Disease
More than two-thirds of patients experienced a more than 5% weight loss with 12 months of etelcalcetide treatment.
Hypertension, Albuminuria Common in Pediatric Type 2 Diabetes
The prevalence of hypertension and albuminuria in pediatric patients with type 2 diabetes varies by race.
Kidney Disease in SLE Possible Despite Low-Level Proteinuria
Based on new findings from a study of patients with systemic lupus erythematosus, investigators suggest revising current guidelines to expand kidney biopsy indications to include isolated proteinuria of any grade.
Intensive Urate-Lowering May Protect Kidneys in Type 2 Diabetes
The effects of combined verinurad and febuxostat treatment were independent of blood pressure.
Corticosteroids-Cyclophosphamide May Be Superior for Primary MN
In a trial of patients with primary membranous nephropathy, corticosteroid-cyclophosphamide induced significantly more and faster remission of nephrotic syndrome than tacrolimus-rituximab.
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