Non-Standard Therapies Used in 20% of Localized High-Risk PCa Cases
Using EBRT alone or ADT alone for high-risk localized prostate cancer is associated with worse survival outcomes.
Prostatectomy
Prostate Cancer Recurrence Risk Higher With Extensive Positive Margins
In a study, just 12.1% of cases with focal positive surgical margins (PSM) experienced biochemical recurrence compared with 54.1% of those with extensive PSM.
Prostate Cancer Mortality Lowest With Radical Prostatectomy
In a study with a follow-up period of 18 years, men treated with any other modality but radical prostatectomy had higher prostate cancer death risks.
Younger Men With High-Grade PCa Less Likely to Die After RP Than RT
Patients younger than age 60 with Gleason 8-10 disease who had upfront surgery versus radiation therapy had a 63% lower risk of prostate cancer-specific mortality.
Radical Prostatectomy Has Lasting Benefit for Localized Cancer
Mean 2.9 years gained after 23 years of follow-up among men with localized prostate cancer
Salvage RARP Feasible, Effective
According to researchers, 57.3% of men who underwent salvage robot-assisted radical prostatectomy were pad-free at 12 months.
PIVOT Study Results Challenged
Researchers question the generalizability of a major study showing no significant difference in cancer-specific and overall survival between surgery and observation for localized prostate cancer.
Gleason Score at Surgical Margin Affects BCR Risk
Gleason score at the margin can better stratify biochemical recurrence-free rates, according to study findings.
More Extensive Lymph Node Dissection in PCa Improves Outcomes
Study shows that the risk of recurrence after salvage radiotherapy is inversely related to the number of nodes resected at radical prostatectomy.
Perioperative Aspirin Use Need Not Prevent RP
Perioperative aspirin use should not be considered an absolute contraindication to radical prostatectomy (RP).
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