Black men may be getting the message that they are at increased risk of prostate cancer, according to a study published in Cancer Epidemiology, Biomarkers & Prevention (2008;17:636-644).
Gray-scale transrectal ultrasonography (TRUS) alone has a limited potential to detect prostate cancer, particularly in patients with total PSA levels below 20 ng/mL, researchers reported in the Journal of Medical Imaging and Radiation Oncology (2008;52:24-28).
Using an assay they developed to detect antibodies to Propionibacterium acnes bacteria, researchers have found a link between these bacteria and development of inflammation-related prostate diseases.
Hemodilution from increased circulating plasma volumes could explain why obese men with prostate cancer have lower serum PSA levels than non-obese men with the malignancy, according to researchers.
CHICAGO—A new compound that specifically inhibits production of the cell-survival protein clusterin appears to be well tolerated and produces PSA responses when given in combination with docetaxel and prednisone in men with metastatic hormone refractory prostate cancer (HRPC), a study found.