FDA Approves Oral Daprodustat to Treat Anemia in Dialysis
The FDA approval of daprodustat is based on results from the ASCEND-D trial comparing daprodustat with ESAs.
Diagnosis & Disease Information
High-Risk APOL1 Genotype Ups Kidney Failure Risk
Black patients without high-risk APOL1 alleles did not have higher risks for kidney failure.
Risk for GI Bleed Increased With Hemodialysis Versus Peritoneal Dialysis
Furthermore, use of anticoagulants induces higher incidence of GI bleeding in hemodialysis versus peritoneal dialysis patients
Iron Deficiency Without Anemia Common in Peritoneal Dialysis Population
Iron deficiency associates with adverse outcomes in patients on peritoneal dialysis, regardless of anemia status.
COVID-19 Vaccines Reduce Risk of Severe Outcomes in CKD
Vaccination decreased the risk for COVID-related hospitalization and death, according to a retrospective study.
Home Dialysis Rate Did Not Increase Despite Financial Incentives
Higher financial incentives may be necessary to change clinician and facility behavior, investigators suggested.
SLE Flare Can Still Occur After Dialysis Initiation
In a study of 121 patients with lupus nephritis on dialysis, 26.4% experienced an SLE flare at a median of 17 months after dialysis initiation.
SPS, Patiromer Lower Serum Potassium in Hemodialysis
Both potassium binders effectively lowered serum potassium levels in patients on hemodialysis meeting hyperkalemia definitions, compared with no treatment, investigators reported.
Fracture Risk Differs by Kidney Failure Cause
Risk of fracture at specific sites differed by cause of kidney failure, investigators found.
Decrease Noted in Peritoneal Dialysis-Linked Peritonitis Rates
5% decline seen in peritonitis rate per year; rate varied by patient factors, including age, race, prior peritoneal episodes
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