Try Behavioral Therapy First When Treating Overactive Bladder in Men
New study results reinforce OAB guidelines recommending behavioral therapy as first-line treatment.
New study results reinforce OAB guidelines recommending behavioral therapy as first-line treatment.
In a study, users of the older formulation of desmopressin had a 13-fold higher rate of hyponatremia than users of oxybutynin.
Similar proportions of black and white men had each type of nocturia.
Decreasing salt intake may benefit patients with nocturia who are heavy salt users, according to a new study published in Neurourology and Urodynamics. In a prospective study, Tomohiro Matsuo, MD, and colleagues from Nagasaki University Graduate School of Biomedical Sciences in Nagasaki, Japan, analyzed changes in lower urinary tract symptoms in 321 patients with nocturia…
In a small trial, patients receiving 300 U and 500 U of intravesical abobotulinumtoxin A experienced reductions in nocturia episodes at 12 and 24 weeks.
In a study, percutaneous tibial nerve stimulation reduced nocturia episodes by 0.8 on average.
Nocturia improved 43% in patients receiving oral desmopressin alone and 64.3% in those receiving desmopressin and an alpha-blocker.
Desmopressin reduced the number of nocturnal voids by 0.85 compared with placebo.
Men with nocturia have a 1.4-fold greater risk of death than men without nocturia, after adjustment for age and major comorbidities.
The antidiuretic effects of desmopressin are mediated by stimulation of vasopressin 2 (V2) receptors, thereby increasing water reabsorption in the kidneys, and reducing urine production.