The Changing Treatment Paradigm for IgAN
Clinicians have a growing number of options for treating immunoglobulin A nephropathy.
Diagnosis & Disease Information
Zetomipzomib Reduces Proteinuria in Proliferative Lupus Nephritis
Kidney function remained stable throughout the 25 week treatment period.
Conservative Kidney Management Often a Better Option for Older Adults With ESKD
In many cases, older patients with end-stage kidney disease would be better off with conservative kidney management focused on enhancing quality of life rather than going on dialysis.
Kidney Function Stable During 12 Months of Pegloticase-Methotrexate for Gout
Kidney function was not harmed over 52 weeks of pegloticase and methotrexate co-therapy in patients with uncontrolled gout at baseline.
Proteinuria Reduction in IgA Nephropathy Greater With Sparsentan
Sparsentan is a dual endothelin and angiotensin receptor antagonist.
CKD Increases Odds of AKI Requiring Dialysis in Inpatients With Pneumonia
The rate of AKI requiring dialysis among patients hospitalized with pneumonia was 2.5% for those with CKD compared with 0.03% for those without CKD.
Hyperkalemia Recurrence Common in CKD Despite Medical Nutrition Therapy
Medical nutritional therapy may need to be combined with anti-hyperkalemia therapy to prevent recurrence, investigators suggested.
SGLT2 Inhibitor Plus MRA Further Reduces Albuminuria
Study findings indicate synergistic effects of SGLT2 inhibitors and MRAs on albuminuria.
RBC Transfusions Commonly Lead to Hyperkalemia, Hospitalization in CKD
Use of intravenous iron and ESAs was low among patients with stage 3 to 5 CKD.
Upper GI Erosions Are the Most Frequent Non-CV Events in the Dialysis Population
The rate of esophageal and gastric erosions among patients on dialysis eligible for anemia treatment was approximately 49 events per 100 patient-years, investigators report.
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