Case: Recurrent Lupus Nephritis at 12 Years After Kidney Transplantation
Lupus nephritis recurrences, while rare, typically happen within a few years of kidney transplantation.
Diagnosis & Disease Information
Tenapanor May Improve Phosphate Normalization in the Dialysis Population
Tenapanor inhibits the sodium hydrogen exchanger 3 (NHE3), reducing paracellular uptake of phosphate in the intestine.
Voclosporin’s Efficacy Confirmed for All Lupus Nephritis Biopsy Classes
Add-on voclosporin improved complete renal response across all lupus nephritis biopsy classes, with the greatest benefit observed in pure class 3.
Women Have Less Access to Kidney Transplant Waitlist
Interventions may be needed to achieve gender and racial equity in access to kidney transplantation across end-stage renal disease networks in the United States.
Preemptive Therapy May Stop FSGS Recurrence in Kidney Transplant Recipients
Investigators report encouraging results from a small observational study testing the effect of preemptive therapeutic plasma exchange and rituximab in kidney transplant recipients whose primary cause of kidney failure was focal segmental glomerulosclerosis.
APOL1 High-Risk Genotype Increases COVID-19-Related AKI Risk in Blacks
In a study of Black patients with COVID-19, those with 2 APOL1 risk alleles have increased odds of acute kidney injury.
Sodium Bicarbonate May Mitigate Calcium Phosphate Stone Risk in CKD
Oral sodium bicarbonate therapy given to patients with chronic kidney disease increases urinary pH but also increases urinary citrate levels, which may mitigate the risk for calcium phosphate stone formation.
Potassium Binder Use Among Hospitalized Patients With Hyperkalemia
Nearly two-thirds of inpatients with a hyperkalemia diagnosis do not receive potassium binders, according to a contemporary analysis.
ADPKD Progression to End-Stage Kidney Disease Varies by Race/Ethnicity
Autosomal dominant polycystic kidney disease progresses to kidney failure faster in Hispanic patients than in those of other races or ethnicities, a study found.
Investigators Identify Predictors of ESA Use in Nondialysis CKD
An analysis of contemporary ESA utilization among patients with anemia of nondialysis-dependent chronic kidney disease may help identify optimal candidates for treatment.
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