Better renal function preservation is associated with decreased cancer-specific death risk among patients who have an estimated glomerular filtration rate (eGFR) below 85 mL/min/1.73 m2 after surgery for organ-confined renal cell carcinoma, a study found.
Investigators observed no differences in surgery time, blood loss, and hospital stay, with deferred vs upfront cytoreductive nephrectomy.
In a population-based study, PN was associated with improved cancer-specific survival by 56%.
In a meta-analysis, partial and radical nephrectomy were associated with similar long-term overall survival, but cancer-specific survival was better with radical nephrectomy.
The risk of negative renal outcomes, including CKD upgrading, increases along with duration of acute kidney injury following partial nephrectomy
Instillation of an investigational mitomycin gel formulation obviated the need for nephrectomy in nearly half of individuals with low-grade upper tract urothelial carcinoma.
Positive surgical margins in patients undergoing partial nephrectomy for cT1b renal cell carcinoma are associated with worse 5-year recurrence-free and overall survival.
Elevated C-reactive protein levels prior to nephrectomy for renal cell carcinoma is associated with an increased risk of renal impairment, a study found.
Delaying surgery more than 10 weeks after diagnosis of pT3 renal cell carcinoma is associated with increased 5-year mortality risk.
Evidence suggests that starting on systemic drug therapy immediately may be the best approach for some patients with metastatic RCC.
