Sunitinib Timing for mRCC Does Not Affect CN Complication Rates
Investigators observed no differences in surgery time, blood loss, and hospital stay, with deferred vs upfront cytoreductive nephrectomy.
Nephrectomy
Partial Nephrectomy Preferable for T1a RCC
In a population-based study, PN was associated with improved cancer-specific survival by 56%.
PN, RN Offer Comparable Long-Term Survival for T1b RCC
In a meta-analysis, partial and radical nephrectomy were associated with similar long-term overall survival, but cancer-specific survival was better with radical nephrectomy.
Post-Nephrectomy AKI Harms Long-Term Renal Functional Recovery
The risk of negative renal outcomes, including CKD upgrading, increases along with duration of acute kidney injury following partial nephrectomy
Mitomycin Gel for UTUC Has Potential to Avert Nephrectomy
Instillation of an investigational mitomycin gel formulation obviated the need for nephrectomy in nearly half of individuals with low-grade upper tract urothelial carcinoma.
Worse Kidney Cancer Outcomes Linked to Positive Surgical Margins
Positive surgical margins in patients undergoing partial nephrectomy for cT1b renal cell carcinoma are associated with worse 5-year recurrence-free and overall survival.
Elevated CRP Before RCC Surgery Predicts Renal Function Decline
Elevated C-reactive protein levels prior to nephrectomy for renal cell carcinoma is associated with an increased risk of renal impairment, a study found.
Delayed Nephrectomy for pT3 RCC Ups Mortality Risk
Delaying surgery more than 10 weeks after diagnosis of pT3 renal cell carcinoma is associated with increased 5-year mortality risk.
Surgery May Not Be Most Appropriate Frontline Tx in mRCC
Evidence suggests that starting on systemic drug therapy immediately may be the best approach for some patients with metastatic RCC.
Personalized Tx May Extend Life in CKD With Small Renal Tumors
Routine partial nephrectomy yielded longest life expectancy in patients with normal renal function.
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