Diagnosis & Disease Information

Anti-Malaria Drug May Prevent SLE Renal Damage

SAN FRANCISCO—Hydroxychloroquine, a low-risk and inexpensive generic drug originally used to treat malaria, may help prevent kidney damage in patients with systemic lupus erythematosus (SLE), according to new study findings presented here at the American College of Rheumatology (ACR) annual scientific meeting.

Shirish Sangle, MD

Rituximab May Not Halt Progression to ESRD

BOSTON—Rituximab is highly effective for treating resistant systemic lupus erythematosus (SLE), but, in certain patients, the medication does not prevent progression to end-stage renal disease (ESRD), British researchers conclude.

lupus nephritis histology

Race, Ethnicity, and SLE Drugs

BOSTON—Among the various racial and ethnic groups in the United States, Hispanics have the worst response to treatment for proliferative nephritis due to systemic lupus erythematosus (SLE), data show.

Traditional Lupus Nephritis Regimen Best

BOSTON—The traditional cyclophosphamide regimen for lupus nephritis recommended by the National Institutes of Health (NIH) is superior to high-dose immunoablative cyclophosphamide, a recent study suggests.

SLE Nephritis is More Common in Males

BOSTON—Kidney involvement stemming from systemic lupus erythematosus (SLE) may be more common in male than female patients, researchers reported at the annual meeting of American College of Rheumatology.

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