MMF Superior For Crescentric Lupus Nephritis, Data Show
Mycophenolate mofetil (MMF) is more effective as induction therapy than cyclophosphamide (CTX) in patients with crescentric lupus nephritis, Chinese investigators report.
Diagnosis & Disease Information
Anti-Malaria Drug May Prevent SLE Renal Damage
SAN FRANCISCO—Hydroxychloroquine, a low-risk and inexpensive generic drug originally used to treat malaria, may help prevent kidney damage in patients with systemic lupus erythematosus (SLE), according to new study findings presented here at the American College of Rheumatology (ACR) annual scientific meeting.
Managing Lupus Nephritis: An Update
Systemic lupus erythematosus (SLE) is a chronic autoimmune vasculitis that affects 1.5 million people in the United States, with approximately 160,000 new cases each year.
ACE Inhibitor Use Eases SLE
ACE inhibitor use delays development of renal involvement in patients with systemic lupus erythematosus (SLE).
Enteric-Coated Mycophenolate Sodium for Lupus Nephritis
Enteric-coated mycophenolate sodium is effective and well-tolerated in patients with active lupus nephritis, Hong Kong researchers report.
Rituximab May Not Halt Progression to ESRD
BOSTON—Rituximab is highly effective for treating resistant systemic lupus erythematosus (SLE), but, in certain patients, the medication does not prevent progression to end-stage renal disease (ESRD), British researchers conclude.
24-Hour Urine Collection May Be Avoidable
BOSTON—It may be possible to get accurate urine protein excretion estimates in lupus nephritis patients in three or 12 hours instead of 24, according to researchers at Johns Hopkins University in Baltimore.
Race, Ethnicity, and SLE Drugs
BOSTON—Among the various racial and ethnic groups in the United States, Hispanics have the worst response to treatment for proliferative nephritis due to systemic lupus erythematosus (SLE), data show.
Traditional Lupus Nephritis Regimen Best
BOSTON—The traditional cyclophosphamide regimen for lupus nephritis recommended by the National Institutes of Health (NIH) is superior to high-dose immunoablative cyclophosphamide, a recent study suggests.
SLE Nephritis is More Common in Males
BOSTON—Kidney involvement stemming from systemic lupus erythematosus (SLE) may be more common in male than female patients, researchers reported at the annual meeting of American College of Rheumatology.
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