BOSTON—Rituximab is highly effective for treating resistant systemic lupus erythematosus (SLE), but, in certain patients, the medication does not prevent progression to end-stage renal disease (ESRD), British researchers conclude.
BOSTON—It may be possible to get accurate urine protein excretion estimates in lupus nephritis patients in three or 12 hours instead of 24, according to researchers at Johns Hopkins University in Baltimore.
BOSTON—Among the various racial and ethnic groups in the United States, Hispanics have the worst response to treatment for proliferative nephritis due to systemic lupus erythematosus (SLE), data show.
BOSTON—The traditional cyclophosphamide regimen for lupus nephritis recommended by the National Institutes of Health (NIH) is superior to high-dose immunoablative cyclophosphamide, a recent study suggests.
BOSTON—Kidney involvement stemming from systemic lupus erythematosus (SLE) may be more common in male than female patients, researchers reported at the annual meeting of American College of Rheumatology.
WASHINGTON, D.C.—The best predictor of outcome in patients with lupus nephritis is kidney function at the time of renal biopsy, supporting the need for early diagnosis and treatment, researchers reported here at the American College of Rheumatology annual meeting.
Systemic nitric oxide (NO) levels are elevated in patients with proliferative lupus nephritis, researchers found. The association is independent of renal elimination of nitrate and nitrite (NOx), a measure of NO production.
Rituximab (Rituxan), a biologic agent used to treat B-cell non-Hodgkin’s lymphoma, may offer a promising option for treating severe membranous lupus nephritis (MLN), according to Swedish researchers.
Even partial remission of lupus nephritis may be associated with better patient survival and a reduced risk of progressing to end-stage renal disease (ESRD).
Researchers say they have discovered a novel biomarker for renal activity in patients with lupus nephritis. The marking, a cytokine called TWEAK, can be measured with a simple urine test.
