Early Use of RAAS Inhibitors May Benefit Children With Lupus Nephritis
Real-world data on use of RAAS inhibitors can be used to support future pragmatic studies to optimize management of childhood-onset SLE, according to investigators.
Lupus Nephritis
Lupus Nephritis Affects Health-Related Quality of Life
Both renal and extra-renal manifestations of lupus nephritis need to be managed, according to investigators.
Second Biopsy Better Predicts ESKD in Lupus Nephritis
A second biopsy adds valuable information on lupus nephritis course, according to investigators.
SLE Survival Rates Improving, But Lupus Nephritis Risk High Among Non-White Patients
Researchers investigated the patient factors that affect risk for mortality and lupus nephritis among patients with SLE.
Bowman’s Capsule Rupture Linked to Poor Prognosis in Lupus Nephritis
The integrity of Bowman’s capsule may play a role in the progression of lupus nephritis, according to investigators.
Belimumab May Reduce Organ Damage in SLE, Lupus Nephritis
Belimumab is a monoclonal antibody that inhibits B-lymphocyte stimulator.
Infection Risk Varies by Lupus Nephritis Induction Therapy
Adverse effects of induction therapies for lupus nephritis may limit their use.
Clinical Biomarkers of Lupus Nephritis Activity Unreliable
Proteinuria and estimated glomerular filtration rate cannot accurately distinguish between ongoing inflammatory injury and chronic kidney damage in lupus nephritis, investigators pointed out.
Tacrolimus May Be an Alternative for First-Line Lupus Nephritis Therapy
In a study, the calcineurin inhibitor tacrolimus proved to be noninferior to intravenous cyclophosphamide.
International Consensus Developed for Corticosteroid Dosing in Childhood-Onset SLE With Proliferative Lupus Nephritis
Researchers developed a consensus-based standardized corticosteroid dosing regimen for patients with childhood-onset systemic lupus erythematosus with lupus nephritis.
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