SLE Flare Can Still Occur After Dialysis Initiation
In a study of 121 patients with lupus nephritis on dialysis, 26.4% experienced an SLE flare at a median of 17 months after dialysis initiation.
Lupus Nephritis
Incident Cardiovascular Disease Risk Up With Autoimmune Disease
Risk increased progressively with the number of autoimmune diseases present and with younger age
GAPSS Outperforms QRISK in Assessing Cardiovascular Disease Risk in Patients With SLE
Researchers compared the QRISK3 and the adjusted Global AntiPhospholipid Syndrome Score in patients with systemic lupus erythematosus to assess their risk of developing cardiovascular disease.
Reduction in Swollen, Tender Joints Greater With Litifilimab in Lupus
Most secondary end points did not support the results of the analysis for the primary end point
Kidney Failure Predictor in Lupus Nephritis Identified
Persistent isolated C3 hypocomplementemia is associated with an increased risk for end-stage kidney disease or death in patients with proliferative lupus nephritis, a study revealed.
Metabolomics, Lipidomics Identify Systemic Lupus Erythematosus Biomarkers
Researchers sought to integrate serum metabolomics and lipidomics to identify biomarkers of organ involvement in systemic lupus erythematosus.
Novel Biomarkers for Diagnosing Systemic Lupus Erythematosus Detected in Plasma
Researchers evaluated the clinical value of miR-124-3p and miR-337-3p in plasma to determine whether they could serve as biomarkers for systemic lupus erythematosus.
Elevated Blood Pressure a Sign of Kidney Damage in Lupus Nephritis
Hypertension is prevalent among patients with lupus nephritis, especially in those with proliferative disease, investigators noted.
Belimumab Approval Expanded to Include Pediatric Lupus Nephritis
The FDA has expanded the approval of belimumab to include pediatric patients 5 to 17 years of age with active lupus nephritis.
Low-Grade Proteinuria May Warrant Biopsy for Lupus Nephritis
Some patients with SLE and low-grade proteinuria may have early active lupus nephritis.
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