Renal Arteriosclerosis Develops Prematurely in Lupus Nephritis
A study found that renal arteriosclerosis develops 2 decades earlier in patients with lupus nephritis compared with healthy age-matched controls.
Lupus Nephritis
Belimumab Associated With Meaningful Improvement in Lupus Nephritis Trial
GlaxoSmithKline announced positive results from the phase 3 BLISS-LN trial of belimumab for the treatment of active lupus nephritis in adult patients.
Itolizumab Receives Fast Track Status for Lupus Nephritis
The FDA has granted Fast Track designation for itolizumab (EQ001; Equillium) for the treatment of lupus nephritis.
Voclosporin Superior to Standard of Care in Lupus Nephritis Trial
Voclosporin was found to be superior to standard-of-care treatment in patients with lupus nephritis, according to data from the phase 3 AURORA trial.
Biopsy-Informed Management Safely, Accurately Predicts Flares in Lupus Nephritis
This study reports the long-term renal outcomes of kidney biopsies performed at prespecified intervals to determine the safety and accuracy of tapering of maintenance immunosuppression.
Obinutuzumab Gets Breakthrough Status for Treatment of Lupus Nephritis
The Food and Drug Administration (FDA) has granted Breakthrough Therapy designation to obinutuzumab (Genentech), a CD20-directed cytolytic antibody, for the treatment of adults with lupus nephritis. The designation was based on data from the phase 2 NOBILITY study that compared the efficacy and safety of obinutuzumab, in combination with mycophenolate mofetil (MMF) or mycophenolic acid…
Good Renal Transplant Outcomes Reported in Lupus Nephritis Cases
In a small study, patients with lupus nephritis who underwent renal transplantation had 5-year graft and patient survival rates of 76.3% and 92.5%, respectively.
Epidemiologic Study Compares SLE Manifestations in Different Racial Groups
Investigators examined racial/ethnic differences in manifestations of lupus and in the timing and risk of developing severe manifestations.
CDC: Racial Disparity Seen With Lupus-Related Deaths
Deaths among blacks occur sooner after diagnosis and at younger age compared with whites
Adverse Childhood Experiences Linked to Worse Lupus Outcomes
More adverse childhood experiences associated with depression, poor overall health for those with SLE
Next post in Lupus Nephritis
