‘Clinically Negligible’ Residual Kidney Function Still Beneficial
Even at very low levels, residual kidney function in hemodialysis patients clears uremic solutes.
Diagnosis & Disease Information
Rapid Kidney Function Decline in Blacks Linked to Elevated Uric Acid
Each 1 standard deviation in baseline uric acid levels was associated with a significant 80% increased odds of rapid kidney function decline.
Low Urinary Uromodulin Predicts Worse Kidney Outcomes
Patients in the lowest quartiles of urinary uromodulin had increased risks of end-stage renal disease and rapid kidney function decline.
Anemia Raises ESRD Risk in Patients With Chronic Kidney Disease
In a study, end-stage renal disease was 31% more likely to develop in CKD patients with versus without anemia.
Hypertension, Diabetes at Hemodialysis Initiation Increasing
From 1995 to 2015, the prevalence of hypertension and diabetes among patients starting hemodialysis increased from 67.9% to 87.6% and from 43.1% to 59.6%, respectively.
ESRD Frequently Follows Dialysis-Dependent AKI
In a study, end-stage renal disease developed in 56% of patients discharged from a hospital with acute kidney injury requiring dialysis.
Biomarkers Predict Renal Function Decline, CV Events
High levels of parathyroid hormone and fibroblast growth factor 23 in CKD patients are associated with need for renal replacement therapy or a 50% or greater decline in eGFR.
Intensive Home HD, Deceased-Donor Transplants Offer Similar Survival
After adjusting for confounders, patients on intensive home hemodialysis and recipients of deceased-donor kidneys showed no significant difference in death risk
AKI at 12 and 24 Hours After PCI Independently Ups Death Risk
Timing of AKI after urgent percutaneous coronary intervention affects risk of significant kidney function loss 1 year after the procedure.
Anemia Linked to High FGF23 Levels in CKD Patients
CKD patients in the 3rd and 4th quartiles of c-terminal serum fibroblast growth factor 23 had a 74% and 73% higher risk for anemia compared with those in the 1st quartile.
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