Biosimilars Mvasi, Kanjinti Now Available in the US
Mvasi (bevacizumab-awwb), a biosimilar to Avastin (bevacizumab), and Kanjinti (trastuzumab-anns), a biosimilar to Herceptin (trastuzumab) have been made available by Amgen and Allergan.
Kidney Cancer
RCC Ablation Technique Influences Survival Time
One type thermal ablation appeared superior for cT1 a renal cell carcinoma patients.
Managing Immune-Related Cutaneous Adverse Events Due to Immune Checkpoint Inhibitor Therapy
Use of specific immunomodulatory agents is proposed for those with specific corticosteroid-refractory immune-related cutaneous adverse events (ircAEs) based on results of a retrospective analysis.
Sunitinib Timing for mRCC Does Not Affect CN Complication Rates
Investigators observed no differences in surgery time, blood loss, and hospital stay, with deferred vs upfront cytoreductive nephrectomy.
Cytoreductive Nephrectomy Alone for mRCC Linked to Better Survival
Cytoreductive nephrectomy (CN) by itself for metastatic renal cell carcinoma is associated with a 43% decreased risk of death compared with CN plus targeted therapy.
Partial Nephrectomy Preferable for T1a RCC
In a population-based study, PN was associated with improved cancer-specific survival by 56%.
Cancer Survivors Have High Prevalence of Chronic Pain
Prevalence higher for those with less than high school education, low income, public insurance
Study Reveals Lower Predictive Ability for Renal Cancer Models
Prospective validation shows decrease in predictive ability compared with previous retrospective validations
PN, RN Offer Comparable Long-Term Survival for T1b RCC
In a meta-analysis, partial and radical nephrectomy were associated with similar long-term overall survival, but cancer-specific survival was better with radical nephrectomy.
Combination of ICIs and Cytoreductive Surgery in Metastatic RCC Appears Promising
The expression of interferon-related genes in tumor specimens was associated with response to neoadjuvant immune checkpoint inhibitor-based therapy.
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