No Link Found Between Hepatitis C Infection and Extrahepatic Cancers
A study of an Asian population failed to find a link between the virus and malignancies outside of the liver.
Kidney Cancer
Tivozanib Bests Sorafenib in Metastatic Renal Cell Carcinoma
Progression-free survival longer in those receiving tivozanib as third- or fourth-line therapy.
Bone-Targeted Therapies in mRCC May Improve Survival
A small study of patients with metastatic renal cell carcinoma and bone metastases found a trend toward better survival among patients treated with TKIs plus bone-targeted therapies vs those treated with TKIs alone.
Updated Recommendations Issued for Treating Advanced RCC
Axitinib plus pembrolizumab is recommended as first-line therapy for patients with favorable-risk clear cell advanced renal cell carcinoma, according to an updated position statement from the Society for Immunotherapy of Cancer.
Cytoreductive Nephrectomy Offers a Survival Edge in mRCC
Patients receiving modern immunotherapy for metastatic renal cell carcinoma have a decreased risk of death if they also undergo cytoreductive nephrectomy, a study found.
High-Throughput Multichain Immune Repertoire Sequencing for Prediction of Treatment Response in Renal Cell Carcinoma
Next-generation sequencing is being increasingly used to characterize the diversity of T-cell and B-cell receptors in individuals.
Cancer Risk Halved With Bariatric Surgery-Linked Weight Loss
Hazard ratio 0.44 for incident cancer with loss of at least 20 to 35 versus <20% of total body weight.
High Vitamin D Binding Protein Levels Up RCC Risk
The highest vs lowest quartile of vitamin D binding protein was associated with 4.1-fold increased odds of renal cell carcinoma in adjusted analyses.
Microwave Ablation Feasible for cT1b Renal Cell Carcinoma
Microwave ablation for cT1b renal cell carcinoma has outcomes that compare favorably with partial and radical nephrectomy, a study found.
Machine-Based CT May Help Identify BAP1 Mutation Status in Clear Cell Renal Cell Carcinoma
The method could more accurately classify patients with clear cell disease.
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