FDA Needs More Data on Sulopenem for Uncomplicated UTI
The NDA submission was supported by data from the phase 3 SURE1 clinical trial.
Infectious Disease
Natural Immunity to COVID-19 Virus Less Robust in the Dialysis Population
Recent evidence suggests that patients with end-stage kidney disease may not mount as robust an immune response to SARS-CoV-2 as healthy individuals.
Two Doses of COVID-19 Vaccine Appear Necessary to Protect Cancer Patients on Active Treatment
Cancer patients had a low rate of seropositivity after the first vaccine dose but not after the second dose.
Lower SARS-CoV-2 Seroprevalence Found in Unvaccinated Dialysis Population
In January 2021, fewer than 1 in 4 unvaccinated patients receiving dialysis had evidence of past SARS-CoV-2 infection.
Prior Statin Use Linked to Reduced Risk for Death in COVID-19
Risk for death significantly reduced with prior statin and/or antihypertensive use among those with history of CVD and/or hypertension
Complications Develop in Half of COVID-19 Cases Treated in Hospitals
COVID-19 severity at hospital admission predicts complications even in young adults and those without pre-existing health conditions.
Management of COVID-19 in Transplant Recipients Evolved During Pandemic
Therapies used to treat COVID-19 in solid organ transplant recipients shifted since the pandemic began
Q&A: Monoclonal Antibodies for COVID-19
The IDSA recommends that antibody therapy should be administered to patients with mild to moderate COVID-19 at high risk for progression to severe disease.
Mortality Risk Factors in Patients With Cancer and COVID-19 Identified
Investigators zero in on mortality risk factors in patients with cancer who contract COVID-19.
Monoclonal Antibodies for COVID-19 Effective for Transplant Patients
Favorable outcomes, minimal adverse effects seen in solid organ transplant recipients who received monoclonal antibody therapy for COVID-19.
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