Aortic, Mitral Regurgitation Risk Up With Fluoroquinolone Use
Risk significantly increased for current use and recent use, but not past use within 61 to 365 days
Infection
Bacteremia Risk Increases as Renal Function Decreases
Compared with individuals who had an eGFR (in mL/min/1.73 m2) above 90, those with an eGFR of 30-16 and 15 or below had significant 2.4- and 3.76-fold increased risks of bacteremia.
Four Clinical Phenotypes Identified for Sepsis
Phenotype distributions similar in derivation, validation cohorts; highest mortality for γ phenotype
CRBSI Clinical Presentation Varies by Causative Pathogen
Patients with Staphylococcus aureus catheter-related bloodstream infections are the most likely to present with fever, rigor, or both, a study found.
Longer Duration of Antibiotic Use Tied to Risk for CVD in Women
Risk for cardiovascular disease increased for women in middle, late adulthood with longer antibiotic use
Guidelines for Asymptomatic Bacteriuria Updated
Screening for, treating ASB not recommended for infants, children, functionally impaired seniors
High-Dose Flu Vaccine May Cut Hospitalization in Dialysis Patients
Significant reduction seen in hospitalization with receipt of high-dose versus standard-dose vaccine.
IV Iron Therapy in CKD Increases Infection Risk
In a study, IV iron was associated with twice the risk for infections in CKD.
High-Dose Influenza Vaccination May Benefit Transplant Recipients
Double-dose influenza vaccine is safe and may increase antibody response in solid-organ transplant recipients
Hepatitis C Infection May Hasten Chronic Kidney Disease Progression
Patients with both CKD and hepatitis C virus infection are at nearly 2-fold higher risk of end-stage renal disease with those who have CKD only.
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