COVID-19 Vaccines Deemed Safe for Renal Cell Carcinoma Patients on Immune Checkpoint Inhibitors
The rate of new or worsening immune-related adverse events was no higher than previously reported.
The rate of new or worsening immune-related adverse events was no higher than previously reported.
The median cancer-specific survival was 56.5 months.
The median time to first onset of key adverse reactions was within 5 months of starting lenvatinib-pembrolizumab.
Nearly half of non-clear cell renal cell carcinoma samples were classified as proliferative.
Patients with smaller target lesions at baseline were more likely to be long-term survivors.
Iodine concentration and Hounsfield units were associated with treatment response and survival.
The seroconversion rate was 92%.
It was previously unknown whether the survival benefits seen with lenvatinib plus pembrolizumab persisted in the long term.
Researchers determined that few patients with poor risk aRCC were receiving first-line avelumab plus axitinib.
The monthly incremental cost per survivor relative to sunitinib for nivolumab plus ipilimumab decreased over time from $90,035 for 12 months to $18,881 for 48 months.