Antidepressant, NSAID Identified as Culprits in SIADH Case
The patient noted that she was initiated on naproxen by her primary care physician 2 weeks prior to her presentation.
Hyponatremia
Hyponatremia in COVID-19 Cases Ups In-Hospital Mortality
Each level of worsening hyponatremia among patients hospitalized with COVID-19 was significantly associated with 43% increased odds of dying in the hospital, a study found.
Hyponatremia in Heart Failure Linked to High-Dose Furosemide, Spironolactone
In an observational study, furosemide doses of 250 to 500 mg and spironolactone doses of 50 to 100 mg were independently associated with approximately 14% and 20% increased odds of hyponatremia, respectively.
Furosemide Plus Sodium Chloride Not Helpful in Treating SIAD
Adding furosemide with or without sodium chloride to fluid restriction is not more effective than fluid restriction alone at correcting hyponatremia in patients with the syndrome of inappropriate antidiuresis, a study found.
Hyponatremia Linked to Use of Older Desmopressin Formulation
In a study, users of the older formulation of desmopressin had a 13-fold higher rate of hyponatremia than users of oxybutynin.
Hip Fracture Linked to Chronic Prolonged Hyponatremia in CKD
Among CKD patients older than 60 years, chronic prolonged hyponatremia is associated with 36% increased odds of hip fracture in adjusted analyses, a study found.
Kidney Stones Linked to Hyponatremia
Development of kidney stones is 6.2-fold more likely among patients with persistent hyponatremia than those without a history of hyponatremia.
Urea Appears Safe, Effective for Inpatient Hyponatremia
A novel oral formulation of urea increased plasma sodium levels significantly and was well tolerated, according to investigators.
Hyponatremia Increases Risk of Fracture
AUSTIN, Texas—Hyponatremia isstrongly associated with an increasedrisk of fracture and osteoporosis,according to the findings of a newsystematic review and meta-analysispresented at the National KidneyFoundation’s 2018 Spring ClinicalMeetings. The meta-analysis, which included25 studies, found that hyponatremia,defined as a serum sodium level below135 mmol/L, was associated with 2.7-and 2.5-fold greater odds of fracture inprospective and retrospective studies,respectively,…
Urea Found Safe and Effective for Hyponatremia
Treatment with a novel urea formulation that is available in the United States safely improves plasma sodium levels, small study shows.
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