Patients with gout experienced no clinically significant urate-lowering effects from an 8-week course of a modest dosage of vitamin C.
Systemic review suggests allopurinol can significantly improve estimated glomerular filtration rates.
Many but not all cohort studies examining the relationship between hyperuricemia and CKD outcomes suggest they may be intertwined.
Adverse events included skin rash, gastrointestinal problems, and allopurinol hypersensitivity syndrome.
Gout prevalence is higher among patients with lower average estimated glomerular filtration rates or higher levels of albuminuria