Hyperuricemia Archives - Renal and Urology News

Uncontrolled Gout Ups All-Cause, CV Mortality

By

Natasha Persaud

October 31, 2019

There is increasing evidence to support lower serum uric acid thresholds of at least 6 mg/dL in patients with gout to improve survival.

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Addressing Physician Education to Improve Patient Outcomes in Gout

By

Nicole Clemons

October 31, 2019

Dr Brian LaMoreaux emphasized the importance of screening, addressing manifestations, and physician education in improving patient outcomes in gout.

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Vaccines May Increase Risk for Gout Flares, But Benefits of Vaccination Outweigh Risks

By

Tom Greenhalgh

October 25, 2019

Are patients with gout more likely to experience a flare in the days following vaccination?

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DECT-Detected Cardiovascular Monosodium Urate Deposits More Common in Patients With Gout

By

Emily Pond

October 15, 2019

Researchers assessed coronary calcium score and cardiovascular monosodium urate deposits detected by dual-energy computed tomography in patients with gout vs healthy controls.

Patients are often unaware of their increased CV risk related to RA. One study found 95% of patients with RA stratified as having a high risk of CVD underestimated their risk.17 Data show patients with RA are less likely to report angina symptoms, which increases their chances of an unrecognized MI or sudden cardiac death and decreases their likelihood of getting a needed coronary artery bypass graft.18 Some studies have shown interventions to educate RA patients about their risk of CVD have the potential to increase screening for CV risk by PCPs and treatment.19,20 Results from other studies have been less positive. One trial found although educational interventions improved patients’ understanding of their CV risk and prompted intentions to make lifestyle changes, patients did not carry through with their stated intentions.21 Nevertheless, patients should be made aware of all important aspects of their disease.

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Gout Flare Variation Hinders Reporting in Clinical Trials

By

Hannah Dellabella

September 12, 2019

The study describes the variations of gout flares and assesses the different methods of gout flare reporting in clinical trials.

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Febuxostat Safer Than Allopurinol for Asymptomatic Hyperuricemia

By

Hannah Dellabella

August 23, 2019

The researchers assessed the effects of febuxostat and allopurinol on mortality and adverse reactions in patients with hyperuricemia and gout.

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Gout Increases Risk of Advanced Chronic Kidney Disease

By

Jody A. Charnow

August 28, 2019

In a large study of patients in the United Kingdom, patients with gout had a 29% increased risk of advanced CKD and 210% increased risk of end-stage renal disease compared with patients who did not have gout.

Hemodialysis Patients Face Higher Hip Fracture Risk

Peritoneal Dialysis

High Uric Acid Increases Death Risk in Peritoneal Dialysis

By

Jody A. Charnow

August 9, 2019

In patients on peritoneal dialysis, serum uric acid levels in the highest quintile are associated with a nearly 1.5-fold increased risk of all-cause mortality compared with levels in the third quintile, a study found.

a couple sitting on the couch holding hands

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Gout Risk Factors Typically Similar for Men and Women

By

Hannah Dellabella

July 31, 2019

This systematic review identified several risk factors for the development of gout, with the degree of risk between the sexes predominantly being consistent.

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Crystal Deposition in Patients Meeting Provisional Gout Remission Criteria

By

Rheumatology Advisor Contributing Writer

July 18, 2019

Crystal deposition may still be present in patients with gout who fulfill the provisional gout remission criteria.