Guideline-Concordant Gout Therapy Associated With Improved Arterial Function, Reduced Inflammation
Researchers assessed whether initiating guideline-concordant gout therapy improved arterial function and reduced inflammation.
Hyperuricemia
Increased Risk for Erectile Dysfunction in Patients With Gout
Researchers investigated the association between gout and the risk for erectile dysfunction.
Allopurinol Found Not to Prevent Kidney Disease Progression in Key Populations
In separate randomized controlled trials, allopurinol had no significant effect on kidney function decline.
Clinical Benefit Observed With Colchicine in Hospitalized COVID-19 Patients
The open-label, prospective study (GRECCO-19) assessed the effect of treatment with low-dose colchicine on cardiac and inflammatory biomarkers as well as clinical outcomes.
Updated 2020 American College of Rheumatology Gout Management Guidelines
The American College of Rheumatology developed guidelines for the management of gout, including use of urate-lowering therapy, flare treatment, and lifestyle and medication recommendations.
Azathioprine May Increase Pegloticase Responsiveness in Chronic Refractory Gout
Researchers determined the effect of azathioprine on the frequency of chronic refractory gout among patients who had persistent urate lowering from pegloticase therapy.
Allopurinol Not Associated With Increased All-Cause Mortality in Gout
Researchers evaluated the association between allopurinol use and mortality in patients with gout.
Hyperuricemia and Kidney Disease May Be Predictors of Subsequent Flares in Patients With Gout
Researchers examined the changes in the presentation of incident gout in the last
20 years and determined risk for subsequent gout flares after an initial gout attack.
Serum Urate Does Not Have a Causal Effect on Gout Comorbidity Risk, According to Mendelian Randomization Studies
Researchers reviewed the causal relationships between gout, hyperuricemia, and associated comorbidities.
Hypertension Risk Increases as Uric Acid Levels Rise
Elevated serum uric acid (SUA) levels are associated with development of hypertension and vascular and renal target organ damage, according to a new long-term study. Investigators studied 961 parents and 570 children who were initially healthy at the time of recruitment into the STANISLAS cohort, a single-center familial longitudinal cohort that began recruiting patients in…
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