Effect of Dysfunctional Urate Transporter on Kidney Function Characterized
The ABCG2 transporter drives urate excretion in the kidney and intestine.
Diagnosis & Disease Information
Causal Relationships Between Gout and Hypertension Evaluated
Investigators explored the causality between the liability of gout on hypertension and the liability of hypertension on gout.
Triglyceride-Glucose Index Predicts Hyperuricemia in Diabetic Kidney Disease
Early identification of patients at high risk of hyperuricemia using the triglyceride-glucose index may permit prompt intervention.
Gout Tied With SARS-CoV-2 Breakthrough Infection, Adverse Outcomes
Gout patients are susceptible to breakthrough COVID-19 infection and severe outcomes despite vaccination.
Kidney Disease Among Top Contributors to Excess Death Risk in Veterans With Gout
In addition to cardiovascular disease, gout is associated with an increased risk of dying from genitourinary conditions, such as chronic kidney disease.
Methotrexate Added to Pegloticase for Gout Safe for Kidneys
Investigators report findings from the MIRROR RCT trial, which compared pegloticase plus methotrexate vs placebo for uncontrolled gout.
Novel Febuxostat-Telmisartan Cocrystal May Treat Comorbid Hyperuricemia/Gout and Hypertension
The novel cocrystal of febuxostat and telmisartan was evaluated for the treatment of comorbid hyperuricemia/gout and hypertension.
Trends in Serum Urate Monitoring Assessed Among Patients With Gout Receiving ULT
Researchers used data from the ACR RISE registry to evaluate a treat-to-target approach among patients with gout receiving urate-lowering therapy.
Link Between Gout and Cardiovascular Events – An Interview With Robert Keenan, MD
Based on recent study findings, Robert Keenan, MD, discusses the risk for cardiovascular events among patients with gout.
Urate-Lowering Therapy May Be Renoprotective in Asymptomatic Hyperuricemia
Clinicians currently decide whether or not to prescribe urate-lowering therapies in patients with asymptomatic hyperuricemia.
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