Iron-Based Phosphate Binder Is Effective, Does Not Cause Iron Overload
A study of stable dialysis patients receiving sucroferric oxyhydroxide found no significant changes in hemoglobin, ferritin level, and transferrin saturation.
Hyperphosphatemia
Tighter Phosphate Control in HD May Slow Coronary Artery Calcification
Achieving serum phosphate levels of 3.5 to 4.5 mg/dL vs 5.0 to 6.0 mg/dL in patients on hemodialysis was associated with less coronary artery calcification, study findings suggest.
Elevated Phosphate Worsens Inpatient Outcomes Regardless of Renal Function
In a study of hospitalized patients, increased serum phosphate levels significant increased the risk of acute kidney injury, end-stage renal disease, and death.
Hyperphosphatemia in HD May Raise Risk for Peripheral Artery Disease
In a study of hemodialysis patients, PAD risk increased nonlinearly with serum phosphate level.
Tenapanor May Improve Uncontrolled Hyperphosphatemia
By blocking paracellular phosphate transport, tenapanor added to phosphate binders may improve the hyperphosphatemia management in patients on maintenance dialysis, a study found.
Elevated FGF23 Linked to Mortality in Type 2 Diabetes
In a study, elevated FGF23 was associated with increased risks of major adverse cardiovascular events and mortality in type 2 diabetes patients with normal or mildly impaired kidney function.
Elevated Phosphate May Be Detrimental Even Without CKD
If confirmed, findings from 2 new studies would have important clinical implications for phosphate intake in the general population.
Very-Low-Phosphate Diet Not Superior for Reducing FGF23
In a 2-day dietary intervention study, very-low-phosphate and low-phosphate diets decreased fibroblast growth factor 23 levels to a similar degree in patients on hemodialysis, but the very-low-phosphate diets results in greater lowering of phosphorus levels.
Medication Use Low in Non-Dialysis CKD-MBD
Prescriptions of drugs to treat chronic kidney disease-mineral bone disorders varies widely by country, but it is generally low, a study found.
Ferric Citrate May Lessen Anemia in Advanced CKD
The phosphate binder ferric citrate coordination complex may mitigate anemia, elevated phosphorus, and FGF23 in patients with advanced CKD, new research suggests.
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