RAAS Inhibition Combos May Up Hyperkalemia Risk in Diabetic Kidney Disease
The risk for hyperkalemia was highest with use of steroidal MRAs in combination with other RAASi.
Diagnosis & Disease Information
Creatinine-Based eGFR Alone Inadequate for Drug Dosing in Cancer Population
Serum creatinine-based eGFR used alone overestimates kidney function and can lead to inaccurate dosing of medications in patients with cancer.
RAASi Rechallenge Uncommon After Hyperkalemia, Tied With Adverse Outcomes
Only a subset of patients resume their usual RAASi treatment following a hyperkalemia episode, investigators found.
Hyperkalemia Risk Varies by Antihypertensive Combo for Diabetic Kidney Disease
Antihypertensive regimens that include a mineralocorticoid receptor antagonist carry the highest risk for hyperkalemia.
Antibiotic-Related Sudden Cardiac Death Linked to Dialysis Potassium Gradient
The risks for sudden cardiac death from certain QT-prolonging antibiotics increase with steeper serum to dialysate potassium gradients.
Rates of Hyperkalemia, Other Adverse Events Increase as CKD Progresses
Adverse events rates have been rising over time among patients receiving dialysis, investigators reported.
Nomogram Predicts Hyperkalemia in Moderate to Severe CKD
Patients with CKD at high risk of hyperkalemia based on the nomogram may benefit from intensive monitoring, according to investigators.
Hyperkalemia Recurrence Common in CKD Despite Medical Nutrition Therapy
Medical nutritional therapy may need to be combined with anti-hyperkalemia therapy to prevent recurrence, investigators suggested.
RBC Transfusions Commonly Lead to Hyperkalemia, Hospitalization in CKD
Use of intravenous iron and ESAs was low among patients with stage 3 to 5 CKD.
Finerenone May Provide Cardiovascular Benefits in Stage 4 Diabetic Kidney Disease
Patients with stage 4 diabetic kidney disease are understudied and lack treatment options.
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