High Pain Burden Found in CKD, Dialysis, and Transplant Patients
Routine pain assessments using validated scales are vital to develop personalized management strategies, according to investigators.
Hemodialysis
Visceral Fat Area Better at Predicting CV Outcomes in the HD Population
Visceral fat area was significantly associated with the risk for cardiovascular events and death and all-cause mortality, whereas coronary artery calcification score was not, a study found.
Psoriasis Treatment May Decrease Infection, Death Risk in End-Stage Kidney Disease
Psoriasis may be another risk factor for infectious complications in patients receiving dialysis, according to investigators.
Erythropoietin May Increase Hip Fracture Risk in Hemodialysis Patients
Higher erythropoietin doses may be an independent risk factor for hip fractures in hemodialysis patients, data suggest.
Vadadustat Noninferior to ESA in Efficacy, But Not CV Safety in NDD-CKD
Vadadustat and darbepoetin alfa had similar hematologic efficacy in patients with nondialysis-dependent CKD (NDD-CKD) and those on dialysis, but vadadustat was associated with a higher risk of major adverse cardiovascular events in patients with NDD-CKD.
‘Unprecedented’ Decline in ESKD Incidence Occurred Early in the Pandemic
During weeks 12-19 of 2020, the incidence of end-stage kidney disease decreased 20% compared with the same period in 2017-2019, according to a COVID-19 supplement to the US Renal Data System 2020 annual data report.
DOACs Appear Safer Than Warfarin Across Chronic Kidney Disease Stages
Although more research is needed, data suggest that the cardioprotective effect of direct oral anticoagulants may extend to patients with advanced CKD.
Early Hemodialysis Initiation Linked With Increased Death Risk
Findings from a study of 676,196 adult patients in the US Renal Data System support delaying initiation of hemodialysis.
Adding Cinacalcet Shown Not to Slow Vascular Calcification in Hemodialysis
Overall control of hyperparathyroidism and hyperphosphatemia appeared to be associated with a reduction in left ventricular mass, however.
Study IDs Most Effective Strategies to Reduce Fibroblast Growth Factor 23
Circulating FGF23 starts to rise in early stage CKD before the development of other abnormalities such as high parathyroid and phosphate levels and low calcium and 1,25(OH)2D levels.
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