Uric Acid-Lowering Therapy May Increase Risk for CKD
Study findings do not support initiation of uric acid-lowering therapy to prevent CKD.
Gout
Gout Drug May Cut Mortality in Heart Failure Hospitalizations
In-hospital mortality rate lower for patients with acute heart failure exacerbation who received colchicine for gout flare
SGLT2 Inhibitors Shown to Increase Uric Acid Excretion
Increased uric acid excretion could explain, at least in part, the renoprotective effects of SGLT2 inhibitors.
Hyperuricemia With Diabetes Compounds ESKD, Death Risks
A study conducted in Taiwan is the first to show that hyperuricemia is as risky as diabetes in contributing to ESKD and death risk in patients with stage 3 to 5 CKD.
Changing the Standard of Care: The Case for Combining Pegloticase With Immunomodulatory Agents in Gout
John Botson, MD, provides his perspective on including immunodulatory therapy in combination with pegloticase and encourages clinicians to evolve their standard of care in the treatment of uncontrolled gout.
Colchicine May Lower Risk of CKD Progression
Colchicine, a plant-derived alkaloid, has a broad range of anti-inflammatory effects that interfere with neutrophil function, according to investigators.
Gout Flare Risk and Effect of Colchicine Prophylaxis on Flares After COVID-19 Vaccination
Researchers determined risk for gout flares and the effect of colchicine prophylaxis on flares following COVID-19 vaccination.
Gout Common in Advanced Kidney Disease and Dialysis
Nearly 24% of patients with advanced CKD, including those on dialysis, have gout, according to a study.
The Heart of the Issue in Gout and Associated Cardiac Disease
In recognition of American Heart Month 2022, Jasvinder Singh, MD, evaluates the association between gout and cardiac disease, based on published literature.
Kidney Transplant Function Found to Improve With Allopurinol
Improvement observed in estimated glomerular filtration rate in kidney transplant recipients treated with allopurinol for elevated uric acid.
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