Inaxaplin Reduces Proteinuria in FSGS With APOL1 Variants
Study findings suggest targeted inhibition of APOL1 function can reduce proteinuria.
Diagnosis & Disease Information
Obesity in Glomerulonephritis May Increase Risk for ESKD
Obesity rates in glomerular disease have multiplied more than 10-fold over the last 40 years.
Updated KDIGO Guideline on Lupus Nephritis, Other Glomerular Diseases Released
The management recommendations for lupus nephritis are poised to change significantly in the coming months, a KDIGO committee revealed.
Primary Nephrotic Syndrome Increases ESKD, Cardiovascular Risks
Among the study findings, primary nephrotic syndrome was associated with an excess risk of heart failure hospitalization.
Dapagliflozin Slows FSGS Progression
Dapagliflozin, an oral SGLT2 inhibitor, decreased the risk of progression of focal segmental glomerulosclerosis compared with placebo, a subgroup analysis of the DAPA-CKD trial showed.
Preemptive Therapy May Stop FSGS Recurrence in Kidney Transplant Recipients
Investigators report encouraging results from a small observational study testing the effect of preemptive therapeutic plasma exchange and rituximab in kidney transplant recipients whose primary cause of kidney failure was focal segmental glomerulosclerosis.
Kidney Function in FSGS Improves With Proteinuria Reductions
Each 1-unit reduction in log-transformed urinary protein-creatinine ratio in patients with focal segmental glomerulosclerosis is associated with a 77% decreased risk of end-stage kidney disease, a study found.
Possible Tissue Injury Predictor in Transplant Recipients Found
Researchers may have found a predictor for focal segmental glomerulosclerosis (FSGS) in kidney transplant recipients.
FSGS: Talking Points for the Practicing Nephrologist
Distinguishing primary from secondary focal segmental glomerulosclerosis is crucial because the treatment approaches and therapeutic goals differ.
FSGS May Respond to Arthritis Drug
In a small study, abatacept induced partial or complete remission of focal segmental glomerulosclerosis.
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