Prostate Cancer Grade Migration Documented
Grade group 1 prostate cancers declined as a proportion of all prostate cancers.
Epidemiology
Advanced CKD Prevalence Relatively Low but Rising in HIV Population
A study of 3090 patients with HIV seen at a tertiary care hospital from June 2019 to June 2020 revealed a 1.8% prevalence of advanced chronic kidney disease, an approximately 4-fold increase from 2008-2010.
Cancer Risks, Mortality Vary With CKD Stage
The proportion of patients with chronic kidney disease who die from cancer may be underappreciated.
Metastatic Prostate Cancer Continues to Rise in US
Reduced prostate cancer screening after USPSTF guidance changes may have contributed to an increase in diagnoses of metastatic disease, according to investigators.
ESKD Death Rates Vary Across US Counties
County characteristics explain 18.9% of the variation in ESKD mortality, investigators reported.
Prostate Cancer Diagnoses Plunged During First COVID-19 Lockdown in England
From March 23 to July 4, 2020, the number of men newly diagnosed with prostate cancer dropped 48.3% compared with the corresponding period in 2019, according to investigators.
Decreasing Kidney Function Ups Sudden Cardiac Death Risk
As kidney function decreases, the risk for sudden cardiac death increases, independent of a history of coronary heart disease, hypertension, and diabetes, a study found.
Nonmetastatic CRPC Prevalence, Natural History Explored
The natural history of nonmetastatic castration-resistant prostate cancer (nmCRPC) can serve as a benchmark for advances in imaging and treatment, according to investigators.
CKD Mortality and Resource Use Exceeds That of Nonmetastatic Cancers
Study finds worse outcomes among patients who have CKD but no kidney failure.
Metformin Use Linked to Prostate Cancer Risk
In a large study of men with newly diagnosed diabetes, exposure to metformin in the previous year was associated with an increased risk for a prostate cancer diagnosis, whereas exposure 2 to 7 years previously was associated with decreased risk.
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