Free Fatty Acids Associated With Rapid Decline in Glomerular Filtration Rates in Type 1 Diabetes
Researchers identified lipidomic predictors of rapid decline of kidney function in individuals with type 1 diabetes.
Researchers identified lipidomic predictors of rapid decline of kidney function in individuals with type 1 diabetes.
Dapagliflozin’s benefits among patients with stage 4 CKD were consistent with those observed in the larger DAPA-CKD cohort with stage 2-3 CKD.
Study findings indicate a correlation between iPTH and vascular calcification in patients with diabetic kidney disease.
The approval was based on data from the phase 3 FIDELIO-DKD trial.
Among the patients with high-risk diabetes in the trial, 21.8% had both a history of cardiovascular disease and current kidney disease.
More than one-quarter are classified as rapid decliners, which was more common with type 2 diabetes
Because finerenone inhibits cardiac remodeling in preclinical models, investigators sought to examine its effect on new-onset AFF by analyzing data from the FIDELIO-DKD phase 3 trial.
In a small trial, patients with the highest tertile of IL-6 experienced significantly faster progression of diabetic kidney disease.
Increases in the proportion of red blood cells mediates the reduction in renal risks associated with SGLT2 inhibitor therapy in patients with type 2 diabetes and cardiovascular disease, a study found.
More than two-thirds of patients experienced a more than 5% weight loss with 12 months of etelcalcetide treatment.