Long-Term Risk for Severe Kidney Disease High in Those With T2DM
Onset at younger age with longer diabetes duration may add to risk for end-stage kidney disease.
Diabetic Nephropathy
High Prevalence of Americans Have Conditions Linked to Severe COVID-19
Median prevalence of any underlying medical condition is 47.2% for residents in all 50 states, DC.
Increased Renal ACE2 in Diabetic Nephropathy May Up COVID-19 Kidney Infection Risk
SARS-CoV-2, the virus that causes COVID-19, enters cells by binding to ACE2 on cell surfaces. Investigators performed a comparative analysis of specimens of diabetic kidney disease tissue and healthy tissue for ACE2 expression.
Finerenone Found to Delay Progression of Diabetic Kidney Disease
Early results from the phase 3 FIDELIO-DKD study also show that finerenone reduces the risk for a cardiovascular secondary endpoint in patients with diabetic kidney disease.
Allopurinol Found Not to Prevent Kidney Disease Progression in Key Populations
In separate randomized controlled trials, allopurinol had no significant effect on kidney function decline.
SGLT2 Inhibitors Linked With Lower Risk for Serious Renal Events
Study findings further support the use of SGLT2 inhibitors in a broad range of patients with type 2 diabetes, according to investigators.
Dapagliflozin To Be Evaluated in COVID-19 Patients With Cardiovascular, Metabolic, or Renal Risk Factors
A phase 3 trial to evaluate dapagliflozin, a sodium-glucose cotransporter 2 (SGLT2) inhibitor, as a potential treatment for patients hospitalized with coronavirus disease 2019.
Albuminuria in T2DM Linked to Worse Outcomes in Absence of Known CVD
The risks for major events increased with the degree of albuminuria among patients with type 2 diabetes mellitus and no overt cardiovascular disease.
Bariatric Surgery in Teens May Cut Diabetic Kidney Disease Risk
Decreased rates of hyperfiltration, elevated UAE seen among surgically treated obese teens with T2DM.
Patiromer Effective Up to 1 Year in Advanced Diabetic Kidney Disease
In a 52-week study, daily treatment with patiromer maintained normokalemia in patients, regardless of age.
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