Allopurinol Found Not to Prevent Kidney Disease Progression in Key Populations
In separate randomized controlled trials, allopurinol had no significant effect on kidney function decline.
Diabetic Nephropathy
SGLT2 Inhibitors Linked With Lower Risk for Serious Renal Events
Study findings further support the use of SGLT2 inhibitors in a broad range of patients with type 2 diabetes, according to investigators.
Dapagliflozin To Be Evaluated in COVID-19 Patients With Cardiovascular, Metabolic, or Renal Risk Factors
A phase 3 trial to evaluate dapagliflozin, a sodium-glucose cotransporter 2 (SGLT2) inhibitor, as a potential treatment for patients hospitalized with coronavirus disease 2019.
Albuminuria in T2DM Linked to Worse Outcomes in Absence of Known CVD
The risks for major events increased with the degree of albuminuria among patients with type 2 diabetes mellitus and no overt cardiovascular disease.
Bariatric Surgery in Teens May Cut Diabetic Kidney Disease Risk
Decreased rates of hyperfiltration, elevated UAE seen among surgically treated obese teens with T2DM.
Patiromer Effective Up to 1 Year in Advanced Diabetic Kidney Disease
In a 52-week study, daily treatment with patiromer maintained normokalemia in patients, regardless of age.
SGLT2 Inhibitors Linked to Less Renal Deterioration Across All CKD Stages
Treatment with SGLT2 inhibitors empagliflozin and dapagliflozin may be associated with less decline in kidney function across different chronic kidney disease stages.
Tx Choice for T2DM in Obese Teens Tied to Later Kidney Disease Risk
Odds of diabetic kidney disease higher in obese teens receiving medical therapy versus bariatric surgery for T2DM
Spironolactone Does Not Prevent Diabetic Nephropathy in Type 2 Diabetes
In a study, spironolactone treatment was not significantly better than placebo in preventing diabetic nephropathy in patients with high-risk type 2 diabetes.
Canagliflozin Protects Against Renal Function Decline in Advanced Diabetic CKD
WASHINGTON—Canagliflozin showed a protective effect against kidney function decline in patients with type 2 diabetes and a baseline estimated glomerular filtration rate (eGFR) below 30 mL/min/1.73 m2, new study findings presented at the American Society of Nephrology’s Kidney Week 2019 meeting suggest. The findings are from a post-hoc subgroup analysis of the phase 3 CREDENCE…
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