Esaxerenone Improves Microalbuminuria in Type 2 Diabetes
In a phase 2 study of patients with early diabetic nephropathy, esaxerenone decreased microalbuminuria in a dose-dependent manner over 12 weeks compared with placebo.
Diabetic Nephropathy
Dulaglutide Reduces CV Events, Renal Progression in Type 2 Diabetes
In the REWIND trial of type 2 diabetes patients, dulaglutide modestly reduced cardiovascular events and progression of kidney disease for at least 5 years.
Ertugliflozin Linked to Better Renal Function in Type 2 Diabetes
Ertugliflozin may be protective of renal function in patients with type 2 diabetes.
Dapagliflozin Shown to Slow Diabetic Kidney Disease Progression
Protective effect is driven largely by a sustained 40% decrease in estimate glomerular filtration rate to below 60 mL/min/1.73 m2.
ADA Updates Diabetic Nephropathy Recommendations
Per the ADA update, clinicians should consider prescribing a SGLT2 inhibitor in type 2 diabetes patients with diabetic nephropathy.
Nearly Half of Type 2 Diabetics Have Undiagnosed CKD
Undiagnosed chronic kidney disease is present in 49% of patients with type 2 diabetes mellitus in the United States, a study found.
Atrasentan Tied to Lower Risk for Kidney Events in T2DM With CKD
Reduced risk seen for primary composite renal end point event; more frequent fluid retention, anemia reported
Nondihydropyridine CCBs May Be an Effective Treatment Option for Proteinuria in Certain Patients
Nondihydropyridine calcium channel blockers (non-DHP CCBs) appear to reduce proteinuria in patients with diabetic kidney disease
Canagliflozin Lowers ESRD Risk in Diabetic Kidney Disease
In a study of patients with type 2 diabetes and chronic kidney disease, canagliflozin, an SGLT2 inhibitor, decreased the risk of end-stage renal disease by 32% compared with placebo.
Higher Glucose Levels at Dialysis Transition Increase Mortality Risk
New findings suggest that diabetic patients with advanced chronic kidney disease may need different glucose control strategies depending on whether or not they are transitioning to dialysis.
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