Obesity, Hyperglycemia Potentiate Family History’s Effect on Kidney Cancer Risk
Both genetic and lifestyle factors interact to increase the risks for renal cell carcinoma, investigators reported.
Diagnosis & Disease Information
High Oxalate Ups Cardiovascular Risks in Diabetics on Hemodialysis
The highest vs lowest quartile of serum oxalate levels were significantly associated with 40% and 62% increases risks for serious cardiovascular events and sudden cardiac death, respectively.
Efpeglenatide Improves Renal, Cardiovascular Outcomes in High-Risk Diabetes
Among the patients with high-risk diabetes in the trial, 21.8% had both a history of cardiovascular disease and current kidney disease.
Admission Hyperglycemia Predicts Mortality in COVID-19
Patients with hyperglycemia had higher cumulative probability of mortality, independent of preexisting diabetes
Antimalarials May Cut Risk for Type 2 Diabetes in Lupus Patients
T2DM risk reduced by 39 percent for those with high adherence to antimalarial therapy for managing lupus.
Frailty Ups Urinary Stone Risk in Diabetics
New findings suggest that it may be possible to direct interventions toward frailty to ameliorate urolithiasis risk in patients with diabetes.
Metformin Use Associated With Lower Death Risk in Type 2 Diabetes
In a study of patients with type 2 diabetes at high cardiovascular (CV) risk, metformin use decrease the risk of all-cause mortality but had no significant effect on a composite end point of CV death, MI, or ischemic stroke.
Dapagliflozin Shown to Slow Diabetic Kidney Disease Progression
Protective effect is driven largely by a sustained 40% decrease in estimate glomerular filtration rate to below 60 mL/min/1.73 m2.
FDA Grants Priority Review for Canagliflozin to Treat CKD in T2DM
If approved, canagliflozin would be the first drug in almost 20 years indicated to treat CKD in patients with type 2 diabetes when added to current standard of care, according to the drug’s maker.
GFR Decline Tied to Protein Intake in Diabetic Blacks
The percentage decline in estimated glomerular filtration rate over an 8-year period was greater among those with vs without diabetes across all quintiles of protein intake.
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