AKI More Likely After Intracoronary Versus IV Contrast Delivery
In a phase 3 trial, acute kidney injury developed in 13.2% of patients undergoing invasive coronary angiography compared with 5.6% of those undergoing computed tomography angiography.
Contrast-Induced Nephropathy
AKI After Computed Tomography Not Tied to Contrast
AKI occurred with similar frequency among patients who did and did not receive contrast medium.
Post-PCI Acute Kidney Injury Not Linked to Contrast Use
Myocardial infarction patients who underwent percutaneous coronary intervention had an AKI rate similar to those who did not have the procedure.
Risk Factors for Contrast-Induced AKI in Transplant Patients ID’d
Risk factors include impaired renal function and inadequate hydration prior to contrast exposure.
Study Questions Prophylactic Hydration as Standard Care for CIN
High-risk patients who did not receive guidelines-recommended prophylactic hydration prior to procedures requiring iodinated contrast media had the same rate of contrast-induced nephropathy (CIN) as patients who received usual care, according to results from the phase 3 AMACING trial published online ahead of print in The Lancet.1 CIN refers to the decline in renal function…
AKI Risk Associated With Radiocontrast May Be Overestimated
In a study, the odds of acute kidney injury were 7% lower among patients who received radiocontrast versus those who did not.
Low Hemoglobin Associated With Elevated Risk of CIN
CIN developed in 14.7% of patients with low hemoglobin levels compared with 5% of those with normal levels.
N-Acetylcysteine May Protect Against CIN
N-acetylcysteine patients had significantly decreased odds of contrast-induced nephropathy.
Reduced Risk of Contrast-Induced Nephropathy With Iodixanol
Greatest reduction for N-acetylcysteine in patients receiving low-osmolar contrast media.
New Findings May Improve Prediction of Contrast-Induced Nephropathy
Risk is linked to small changes in serum creatinine and eGFR on the day after contrast exposure.
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