Hepcidin May Enable Early Ruling Out of Contrast-Induced AKI
Serum hepcidin rises significantly as early as 4 and 8 hours after percutaneous coronary intervention.
Contrast-Induced Nephropathy
Acute Kidney Injury Risk Lower With Ultra-Low Contrast Volume Use
Use of ultra-low contrast volume during percutaneous coronary intervention was associated with 32% decreased odds of acute kidney injury, investigators report.
Ultra-low Contrast Volume May Protect Kidneys in Advanced CKD
No patient had a 25% or greater rise in serum creatinine 48 hours after receiving a median 13 mL of contrast for diagnostic coronary angiography, with an additional 13 mL for percutaneous coronary intervention.
IV Sodium Bicarbonate Does Not Reduce AKI Risk After Angiography
Contrast-associated acute kidney injury occurred in 9.5% and 9.1% of patients receiving IV sodium bicarbonate and acetylcysteine, respectively, rates which did not differ significantly from the 8.3% rate among those receiving IV sodium chloride.
AKI More Likely After Intracoronary Versus IV Contrast Delivery
In a phase 3 trial, acute kidney injury developed in 13.2% of patients undergoing invasive coronary angiography compared with 5.6% of those undergoing computed tomography angiography.
AKI After Computed Tomography Not Tied to Contrast
AKI occurred with similar frequency among patients who did and did not receive contrast medium.
Post-PCI Acute Kidney Injury Not Linked to Contrast Use
Myocardial infarction patients who underwent percutaneous coronary intervention had an AKI rate similar to those who did not have the procedure.
Risk Factors for Contrast-Induced AKI in Transplant Patients ID’d
Risk factors include impaired renal function and inadequate hydration prior to contrast exposure.
Study Questions Prophylactic Hydration as Standard Care for CIN
High-risk patients who did not receive guidelines-recommended prophylactic hydration prior to procedures requiring iodinated contrast media had the same rate of contrast-induced nephropathy (CIN) as patients who received usual care, according to results from the phase 3 AMACING trial published online ahead of print in The Lancet.1 CIN refers to the decline in renal function…
AKI Risk Associated With Radiocontrast May Be Overestimated
In a study, the odds of acute kidney injury were 7% lower among patients who received radiocontrast versus those who did not.
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