NOACs Show Superiority in Early-Stage Chronic Kidney Disease
Non-vitamin K oral anticoagulants reduce hemorrhagic stroke and intracranial hemorrhage risks vs vitamin K antagonists in patients with end-stage renal disease and atrial fibrillation.
Chronic Kidney Disease
RCC in Advanced CKD: A Transplant Dilemma
Non-dialysis patients with advanced CKD diagnosed with renal malignancies grapple with the dual threat of renal failure and cancer progression. When choosing between functional or oncologic risks, many patients will ask about renal transplantation. Discussions of this option are complicated by statistical realities: According to UNOS, of nearly 1 million solid organ transplants performed over…
Study Finds Persistent Gaps in CKD Care
Statin use by kidney disease patients in the United States, for example, is far below recommended levels: just 31% during 2012 to 2014.
CKD Patient Cardiovascular Status Affects Cardiac Care Outcomes
In a study, coronary revascularization was associated with improved survival in high-risk but not low-risk patients with chronic kidney disease patients on Medicare.
Lower Blood Transfusion Threshold During Cardiac Surgery Does Not Raise AKI Risk
Transfusing red blood cells into cardiac surgery patients only when their hemoglobin levels fall to below 7.5 g/dL does not increase acute kidney injury risk.
Pre-ESRD Low Albumin Ups Post-Dialysis Mortality
Serum albumin levels below 2.8 g/dL vs 4.0 g/dL or higher prior to starting dialysis are associated with a 2-fold increased risk of death in the 1 year after transition to dialysis, study finds.
Antiviral Therapy May Slow Renal Function Decline in Hepatitis C
In a study, hepatitis C patients with stage 3 CKD and no diabetes experienced 4.3- and 1.8-fold improvements in eGFR, respectively, with antiviral therapy.
Evolocumab Safely Reduces Risk for CV Events in Chronic Kidney Disease
PCSK9 inhibition with evolocumab was safe and more effective than statin monotherapy in reducing LDL-C in stable individuals with moderate CKD and clinically evident atherosclerosis.
Nondrinkers With High Uric Acid at Greatest Risk for CKD
Nondrinkers with high serum uric acid levels had nearly 4 times the risk of developing kidney disease than moderate alcohol drinkers with low uric acid levels.
Sodium Bicarbonate for Metabolic Acidosis Slows CKD Progression
Patients with chronic kidney disease and metabolic acidosis treated with sodium bicarbonate experienced decreased risks of a doubling of serum creatinine, initiation of renal replacement therapy, and death.
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