Optimal Difelikefalin Dose Reported for Pruritus in Hemodialysis
In a previous US phase 2 trial, no clear dose response was observed with difelikefalin.
Chronic Kidney Disease
CKD-MBD Tied to Malnutrition-Inflammation Complex Syndrome
A new review highlights the need to simultaneously control CKD-MBD and MICS in patients receiving hemodialysis.
Advanced CKD Prevalence Relatively Low but Rising in HIV Population
A study of 3090 patients with HIV seen at a tertiary care hospital from June 2019 to June 2020 revealed a 1.8% prevalence of advanced chronic kidney disease, an approximately 4-fold increase from 2008-2010.
Therapies to Slow Vascular Calcification in CKD Explored
Promising therapies still need to be further evaluated in clinical trials.
Exercise May Slow Kidney Function Decline in Older Adults
Prescribing physical activity and exercise may be a “potent tool” for clinicians caring for older adults, according to investigators.
Racial Disparities in Home Dialysis Use Documented
To reach the goals of the Advancing American Kidney Health Executive Order, “strategic efforts to care for racial and ethnic minorities” are needed, according to the authors of a new review.
Combining Dapagliflozin and Eplerenone Further Reduces Albuminuria in CKD
Study findings suggest the nephroprotective effects of both drug classes are complementary.
Underuse of Diabetic Kidney Disease Therapies Reported
Study findings highlight an “unmet need” for newer therapies.
Colchicine May Lower Risk of CKD Progression
Colchicine, a plant-derived alkaloid, has a broad range of anti-inflammatory effects that interfere with neutrophil function, according to investigators.
Uremic Solutes Tied With Cardiovascular Death in Diabetic Kidney Disease
Investigators focused on the prognostic value of the uremic solutes asymmetric dimethylarginine, symmetric dimethylarginine, and trimethylamine-N-oxide.
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