Algorithm Proposed to Expand Cisplatin Eligibility for MIBC
A new algorithm developed by Canadian investigators aims to address underuse of cisplatin-based chemotherapy for muscle-invasive bladder cancer.
Chemotherapy
Radiation for Abdominal, Pelvic Cancers Ups Secondary Sarcoma Risk
Compared with patients who undergo surgery alone for abdominal or pelvic cancers, those who receive radiation and chemotherapy are at elevated risk for secondary sarcomas.
How Cancer Care Can Affect the Kidney
Recent advances in cancer management may present challenges for nephrologists.
Routine Use of Neoadjuvant Docetaxel Plus ADT Not Supported in Localized, High-Risk Prostate Cancer
Patients with localized prostate cancer characterized by high-risk features are at increased risk of a negative outcome following radical prostatectomy.
New Evidence Supports Update of ASCO Guidelines on Prevention, Treatment of CIPN
A literature search of new studies clarifies, refutes, and expands on previous recommendations for managing new and established CIPN in patients treated with cytotoxic agents.
Assessing Barriers and Facilitators of Timely Chemotherapy Delivery in the Ambulatory Care Setting
Researchers examined causes of avoidable chemotherapy delays as a means of improving the quality of care for outpatients receiving chemotherapy.
OS Benefit Seen for Disease Downstaging With Neoadjuvant Chemotherapy vs Transurethral Resection in Muscle-Invasive Bladder Cancer
Two approaches to downstaging muscle-invasive bladder cancer prior to radical cystectomy include neoadjuvant chemotherapy and transurethral resection.
Adding Chemo to Radiation Treatment for MIBC Does Not Worsen HRQoL
Findings from a large study of bladder-sparing treatments for muscle-invasive bladder cancer support the routine use of 5-fluorouracil and mitomycin C concomitantly with radiation therapy.
NAC Prior to UTUC Surgery Suggests Clinical Benefit
In a phase 2 trial, more than half of patients who received neoadjuvant chemotherapy for high-risk upper tract urothelial carcinoma had a pathologic response that was associated with improved survival.
AKI Risk High in Cancer Patients Receiving Systemic Therapy
In a study, nearly 1 in 10 cancer patients on systemic therapy experienced an episode of acute kidney injury.
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