Cardiovascular Disease Archives - Renal and Urology News

Cardiovascular Disease

Twice-Yearly Cholesterol-Lowering Therapy Effective in Phase 3 Trial

The Medicines Company announced topline results from the pivotal phase 3 ORION-11 study that evaluated the efficacy and safety of inclisiran, an investigational twice-yearly cholesterol-lowering therapy. Inclisiran is a chemically synthesized small interfering RNA (siRNA) that targets proprotein convertase subtilisin-kexin type 9 (PCSK9) messenger RNA. The subcutaneous (SC) injectable is being investigated for its ability…

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