QTc Interval Prolonged in Some Hospitalized With COVID-19
QTc prolongation seen in association with age 80 years and older, severe chronic kidney disease, elevated hs-troponin levels
Cardiovascular Disease
Assessing HDL Anti-Inflammatory Capacity May Aid CV Risk Prediction
HDL anti-inflammatory capacity associated with cardiovascular disease events independent of cholesterol efflux capacity
Spironolactone Significantly Reduced Blood Pressure in Older Patients at Risk for Heart Failure
Lower renin levels at baseline predicted a greater BP response to spironolactone.
Preeclampsia Linked to Increased Stroke Risk in Later Life
Association only evident when adjustment was made for all vascular risk factors over the life course
Farxiga Approved for Patients With CKD at Risk of Progression
The approval was based on data from the DAPA-CKD trial, which compared dapagliflozin, an SGLT2 inhibitor, to placebo on renal outcomes and cardiovascular mortality in patients with CKD.
Pulmonary Hypertension May Up Risk for ESKD, Hospitalization, Death in CKD
The association of pulmonary hypertension with an increased risk for kidney failure in older adults with chronic kidney disease is a novel finding.
Prostate Cancer ADT Not Linked to Greater Cardiovascular Mortality
Androgen deprivation therapy added to radiation therapy (RT) for unfavorable-risk prostate cancer is not associated with an increased risk for cardiovascular mortality compared with RT alone, even among patients with preexisting cardiovascular disease, a study found.
Intraabdominal Fat Ups Health Risks in Absence of Obesity
Interventions investigated to reduce these adipose tissue depots, with lifestyle interventions as effective as medications (or more so)
Vadadustat Noninferior to ESA in Efficacy, But Not CV Safety in NDD-CKD
Vadadustat and darbepoetin alfa had similar hematologic efficacy in patients with nondialysis-dependent CKD (NDD-CKD) and those on dialysis, but vadadustat was associated with a higher risk of major adverse cardiovascular events in patients with NDD-CKD.
VTE Risk High in Cancer Patients Receiving Immune Checkpoint Inhibitors
History of VTE predicts VTE occurrence; VTE occurrence linked to increased mortality
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