Adynamic Bone Disease Prevalent in Type 2 Diabetes Patients With CKD
Almost 40% of pre-dialysis patients with stage 4-5 CKD patients and type 2 diabetes had lab results suggesting low turnover bone disease.
Almost 40% of pre-dialysis patients with stage 4-5 CKD patients and type 2 diabetes had lab results suggesting low turnover bone disease.
Among other changes, the new KDIGO guidelines highlight the potential dangers of hypercalcemia.
Researchers using spectral computed tomography found that calcium concentration increased in cortical bone and decreased in cancellous bone.
Bone expression of sclerostin and parathyroid hormone receptor-1 increased in earlier stages of CKD, whereas FGF-23 and phosphorylated b-catenin showed increased expression in later stages.
Alkaline phosphatase was more strongly linked to mortality compared with other biomarkers of chronic kidney disease-mineral and bone disorder.
At 6 months of treatment, bone imaging showed stable disease in 94% of patients with available data, study finds.
Older men on TRT versus placebo for 1 year had improved hemoglobin levels and volumetric bone mineral density and estimated bone strength.
Adipose tissue may be more important than vitamin D intake, new study suggests.
In a study, 94.1% of total PTx patients had improvement of bone mineral density at their most affected site.
Fracture incidence within a year of transplant was 3 times lower among patients who had surgery from 2009 to 2011 vs 2004 to 2006.