Prostate Cancer Detection Greater With Targeted Plus Systematic Biopsy
In a study, combining targeted and systematic biopsy detected 11% to 33% more prostate cancers than either method alone.
Biopsy
Fluoroquinolones Tied to Increased Risk for Arrhythmia, CV Mortality
To investigate the risk of cardiovascular adverse effects associated with this antibiotic class, researchers conducted a systematic review, meta-analysis, and network meta-analysis using studies identified through a search of MEDLINE, EMBASE, and the Cochrane Library.
Prostate Biopsy Complications Deter Patients From Re-Biopsy
Study participants with acute urinary retention after TRUS-guided prostate biopsy were 4.5 times more likely to skip a recommended re-biopsy than men who had no initial biopsy-related complications.
Negative Confirmatory Biopsy Predicts Lower PCa Progression Risk
Men on active surveillance for prostate cancer who had a negative confirmatory biopsy experienced an 88% decreased risk of progression to treatment.
Fosfomycin Tops Fluoroquinolones for Prostate Biopsy Prophylaxis
In a meta-analysis, the risk of infectious complications was 78% lower with fosfomycin trometamol versus fluoroquinolones in men undergoing TRUS-guided prostate biopsy.
Routine Office Urine Culture Before Prostate Biopsy Is Unnecessary
In a single center study, asymptomatic bacteriuria resolved before prostate biopsy, without additional treatment.
Is It Safe to Avoid Biopsy in Men With Elevated PSA?
Multiparametric magnetic resonance imaging in conjunction with transrectal ultrasound-guided biopsy improves discrimination between clinically significant and insignificant prostate tumors and can spare patients unnecessary biopsies.
Repeat Prostate Biopsies Do Not Raise Risk of Post-RP Complications
Rates of erectile dysfunction and urinary incontinence at 1, 2, and 3 years after radical surgery are not higher among men who have multiple prostate biopsies while on active surveillance for prostate cancer.
Structured Investigation of Outpatient Transperineal Prostate Biopsy
The transperineal approach to prostate biopsy has recently been adopted at many centers as an alternative to TRUS-B.
Less Frequent Biopsies May Be Appropriate for PCa Active Surveillance
Investigators who compared 4 active surveillance cohorts found that biennial prostate biopsies appear to be an acceptable alternative to annual biopsies.
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